BDB335787
CD8 Mouse anti-Human, PE-Cy7, Clone: SK1, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB335787-Each-of-1 | In Stock | ₹ 57,838.56 |
BDB335787 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 57,838.56
GST (18%): ₹ 10,410.941
Total Price: ₹ 68,249.501
Antigen
CD8
Classification
Monoclonal
Concentration
50μg/mL
Formulation
Phosphate buffered saline with gelatin and 0.1% sodium azide.
Immunogen
Human Peripheral Blood T Cells
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Applications
Flow Cytometry
Clone
SK1
Conjugate
PE-Cyanine7
Host Species
Mouse
Quantity
100 Tests
Research Discipline
Immunology
Target Species
Human
Isotype
IgG1 κ
Description
- CD8 recognizes the 32-kilodalton (kd) α-subunit of a disulfide-linked bimolecular complex.The majority of peripheral blood CD8+ T lymphocytes expresses an α/β heterodimer (Mr 32, 30 kd), while CD8+ CD16+ natural killer (NK) lymphocytes and CD8+ T-cell receptor (TCR)-γ/δ + T lymphocytes express an α/α homodimer (Mr 30 kd)
- CD8+ TCR-α/β+ T lymphocytes can express either an α/α homodimer or α/β heterodimer
- The CD8 antigenic determinant binds to class I major histocompatibility (MHC) molecules, resulting in increased adhesion between the CD8+ T lymphocytes and target cells.Binding of the CD8 antigen to class I MHC molecules enhances the activation of resting T lymphocytes.The CD8 antigen is coupled to a protein tyrosine kinase, p56 lck
- The CD8:p56 lck complex can play a role in T-lymphocyte activation through mediation of the interactions between the CD8 antigen and the CD3/TCR complex
- The CD8 antigen is present on the human suppressor/cytotoxic T-lymphocyte subset as well as on a subset of NK lymphocytes.The CD8 antigen is expressed on 19% to 48% of normal peripheral blood lymphocytes and 60% to 85% of normal thymocytes.The CD8+ T- and NK-lymphocyte subsets can be further subdivided into the following groups: CD16+ NK lymphocytes that can express the CD8 antigen in low density;CD57+ T lymphocytes that express high-density CD8 antigen;and CD8+CD62L+ lymphocytes that collaborate with CD8+ CD62L-lymphocytes to generate suppression of B-lymphocyte function.CD8 cross-reacts with lymphocytes of some nonhuman primate species Flow Cytometry
Compare Similar Items
Show Difference
Antigen: CD8
Classification: Monoclonal
Concentration: 50μg/mL
Formulation: Phosphate buffered saline with gelatin and 0.1% sodium azide.
Immunogen: Human Peripheral Blood T Cells
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Applications: Flow Cytometry
Clone: SK1
Conjugate: PE-Cyanine7
Host Species: Mouse
Quantity: 100 Tests
Research Discipline: Immunology
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD8
Classification:
Monoclonal
Concentration:
50μg/mL
Formulation:
Phosphate buffered saline with gelatin and 0.1% sodium azide.
Immunogen:
Human Peripheral Blood T Cells
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Applications:
Flow Cytometry
Clone:
SK1
Conjugate:
PE-Cyanine7
Host Species:
Mouse
Quantity:
100 Tests
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD38
Classification: Monoclonal
Concentration: 25μg/mL
Formulation: Phosphate buffered saline with gelatin and 0.1% sodium azide.
Immunogen: Human BJAB B cell line
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Applications: Flow Cytometry
Clone: HB7
Conjugate: PE-Cyanine7
Host Species: Mouse
Quantity: 100 Tests
Research Discipline: Immunology
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD38
Classification:
Monoclonal
Concentration:
25μg/mL
Formulation:
Phosphate buffered saline with gelatin and 0.1% sodium azide.
Immunogen:
Human BJAB B cell line
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Applications:
Flow Cytometry
Clone:
HB7
Conjugate:
PE-Cyanine7
Host Species:
Mouse
Quantity:
100 Tests
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD56
Classification: Monoclonal
Concentration: 25μg/mL
Formulation: Phosphate buffered saline with gelatin and 0.1% sodium azide.
Immunogen: Immunoaffinity-enriched adult human brain NCAM
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Applications: Flow Cytometry
Clone: NCAM16.2
Conjugate: PE-Cyanine7
Host Species: Mouse
Quantity: 100 Tests
Research Discipline: Immunology
Target Species: Human
Isotype: IgG2b κ
Antigen:
CD56
Classification:
Monoclonal
Concentration:
25μg/mL
Formulation:
Phosphate buffered saline with gelatin and 0.1% sodium azide.
Immunogen:
Immunoaffinity-enriched adult human brain NCAM
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Applications:
Flow Cytometry
Clone:
NCAM16.2
Conjugate:
PE-Cyanine7
Host Species:
Mouse
Quantity:
100 Tests
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG2b κ
Antigen: CD69
Classification: Monoclonal
Concentration: 50μg/mL
Formulation: Phosphate buffered saline with gelatin and 0.1% sodium azide.
Immunogen: CD8
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Applications: Flow Cytometry
Clone: L78
Conjugate: PE-Cyanine7
Host Species: Mouse
Quantity: 100 Tests
Research Discipline: Immunology
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD69
Classification:
Monoclonal
Concentration:
50μg/mL
Formulation:
Phosphate buffered saline with gelatin and 0.1% sodium azide.
Immunogen:
CD8
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Applications:
Flow Cytometry
Clone:
L78
Conjugate:
PE-Cyanine7
Host Species:
Mouse
Quantity:
100 Tests
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG1 κ