BDB340536

CD161 Mouse anti-Human, FITC, Clone: DX12, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB340536-Each-of-1 In Stock ₹ 25,496.88

BDB340536 - Each of 1

₹ 25,496.88

In Stock

Quantity

1

Base Price: ₹ 25,496.88

GST (18%): ₹ 4,589.438

Total Price: ₹ 30,086.318

Antigen

CD161

Classification

Monoclonal

Conjugate

FITC

Host Species

Mouse

Quantity

50 Tests

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

DX12

Formulation

Phosphate buffered saline with gelatin and 0.1% sodium azide.

Immunogen

Human NKR-P1A Transfected Mouse Fibroblasts

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

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Description

  • The DX12 monoclonal antibody specifically binds to human CD161 which is also known as Natural killer cell surface protein P1A (NKR-P1A)
  • CD161 is encoded by the KLRB1 (Killer cell lectin-like receptor subfamily B member 1) gene
  • CD161 is a member of the C-type lectin superfamily and is also referred to as C-type lectin domain family 5 member B (CLEC5B)
  • CD161 is a 80 kDa disulfide-linked homodimer, type II membrane glycoprotein
  • CD161 is expressed mostly on NK cell populations and on subsets of CD4+ and CD8+ αβ T cells, NKT cells and γδ T cells
  • Reports indicate that CD161 is expressed preferentially on CD45RO+ T cells, however, it can be found on a subset of thymocytes and fetal liver T cells
  • Its function has not been fully elucidated, but reports indicate that NKR-P1A may serve as a specific receptor for some NK cell targets
  • The DX12 antibody can reportedly inhibit spontaneous cytotoxicity mediated by certain NK cell clones.

Compare Similar Items

Show Difference

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Fischer Scientific

BDB340536

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Antigen:
CD161

Classification:
Monoclonal

Conjugate:
FITC

Host Species:
Mouse

Quantity:
50 Tests

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
DX12

Formulation:
Phosphate buffered saline with gelatin and 0.1% sodium azide.

Immunogen:
Human NKR-P1A Transfected Mouse Fibroblasts

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

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Antigen:
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Classification:
Monoclonal

Conjugate:
APC

Host Species:
Mouse

Quantity:
100 Tests

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
S-HCL-3

Formulation:
Phosphate buffered saline with gelatin and 0.1% sodium azide.

Immunogen:
Human Hairy-Cell Leukemia Cells

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

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Antigen:
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Classification:
Monoclonal

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PE

Host Species:
Mouse

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50 Tests

Research Discipline:
__

Target Species:
Human

Isotype:
IgG1 κ

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Flow Cytometry

Clone:
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Formulation:
Phosphate buffered saline with gelatin and 0.1% sodium azide.

Immunogen:
Human IL-3Rα Transfected Cell Line

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

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Antigen:
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Classification:
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Conjugate:
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Host Species:
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Quantity:
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Research Discipline:
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Target Species:
Human

Isotype:
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Applications:
Flow Cytometry

Clone:
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Formulation:
Phosphate buffered saline with gelatin and 0.1% sodium azide.

Immunogen:
__

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.