BDB551892

CD279 Hamster anti-Mouse, PE, Clone: J43, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB551892-Each-of-1 In Stock ₹ 26,823.06

BDB551892 - Each of 1

₹ 26,823.06

In Stock

Quantity

1

Base Price: ₹ 26,823.06

GST (18%): ₹ 4,828.151

Total Price: ₹ 31,651.211

Antigen

CD279

Classification

Monoclonal

Concentration

0.2mg/mL

Description

PD-1

Host Species

Hamster

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

J43

Conjugate

PE

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Syrian Hamster kidney cell line BKH transfected with Pdcd1 cDNA

Quantity

0.1 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG2 κ

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Description

  • Description The J43 antibody reacts with CD279 (PD-1), a 50-55-kDa glycoprotein encoded by the Pdcd1 gene of the CD28 family of the Ig superfamily
  • The expression of Pdcd1 mRNA and PD-1 protein is tightly regulated
  • PD-1 is transiently expressed on CD4-CD8thymocytes, it is upregulated on some cell lines upon induction of apoptosis, it is induced on thymocytes and splenic T and B lymphocytes after stimulation through their antigen receptors, and it is induced on activated myeloid cells
  • In addition, Pdcd1 mRNA is transiently expressed in developing B lymphocytes at the pro-B-cell stage
  • The presence of an ITIM ( I mmunoreceptor nhibitory M otif) on PD-1's intracytoplasmic region and the development of splenomegaly and breakdown of peripheral tolerance in PD-1[-/-] mice suggest that PD-1 may be involved in the negative regulation of immune responses
  • The PD-1 ligands, B7-H1 (also known as PD-L1) and B7-DC (PD-L2), are members of the B7 family of the Ig superfamily
  • The J43 antibody blocks the binding of PD-1 to its two ligands.

Compare Similar Items

Show Difference

Img

Fischer Scientific

BDB551892

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Antigen:
CD279

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
PD-1

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
J43

Conjugate:
PE

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Syrian Hamster kidney cell line BKH transfected with Pdcd1 cDNA

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2 κ

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BD Biosciences

BDB551899

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Antigen:
CD177

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
NB1

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Applications:
Flow Cytometry

Clone:
MEM-166

Conjugate:
Unconjugated

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
__

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ

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BD Biosciences

BDB551900

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Antigen:
CD32

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
FcγRII

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Applications:
Flow Cytometry

Clone:
3D3

Conjugate:
Unconjugated

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
__

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ

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Antigen:
CD138

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
Syndecan; SDC; Syndecan 1; SDC1; SYND1

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Applications:
Flow Cytometry

Clone:
MI15

Conjugate:
Unconjugated

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Human U266 and XG-1 Myeloma Cell Lines

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ