BDB552476
Syk Mouse anti-Human, FITC, Clone: 4D10, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB552476-Each-of-1 | In Stock | ₹ 31,828.32 |
BDB552476 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,828.32
GST (18%): ₹ 5,729.098
Total Price: ₹ 37,557.418
Antigen
Syk
Classification
Monoclonal
Concentration
0.5mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Human Syk peptide aa. 314-339
Quantity
100 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
4D10
Conjugate
FITC
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2a κ
Related Products
Description
- Syk is a member of the family of non-receptor type protein-tyrosine kinases and plays a crucial role in lymphocyte signaling and development
- Syk is expressed in all haematopoietic cells and contributes to the signal transduction process by binding to a tyrosine-based activation motif (ITAM) of immune receptors, including Igα, TCRζ, CD3ε, FcεRIβ, and FceRIγ
- Upon receptor activation, Syk binds to phosphorylated ITAMs via its two N-terminal SH2 domains thereby activating Syk and causing tyrosines in Syk to undergo auto-phosphorylation or phosphorylation
- These phosphorylated sites can act as binding sites for other signaling molecules or help to regulate enzymatic activity
- For example, in mast cells, Syk can activate downstream targets such as phospholipase Cγ1 and VAV
- Studies in Syk-/- mast cells identified defects in both the ERK-MAP and JNK-MAP kinase pathways
- Syk migrates as 72kDa in SDS/PAGE
- (Predicted MW from SWISS-PROT is 72kDa; Accession number P43405)
- Host Species: Mouse Clone: 4D10 Isotype: IgG2a κ Species Reactivity: Human Immunogen: Human Syk peptide aa
- 314-339 Flow Cytometry
Compare Similar Items
Show Difference
Antigen: Syk
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human Syk peptide aa. 314-339
Quantity: 100 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 4D10
Conjugate: FITC
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2a κ
Antigen:
Syk
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human Syk peptide aa. 314-339
Quantity:
100 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
4D10
Conjugate:
FITC
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2a κ
Antigen: CD275
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human B7-H2
Quantity: 0.1 mg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Flow Cytometry
Clone: 2D3/B7-H2
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Antigen:
CD275
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human B7-H2
Quantity:
0.1 mg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Flow Cytometry
Clone:
2D3/B7-H2
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ
Antigen: CD275
Classification: Monoclonal
Concentration: __
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human B7-H2
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 2D3/B7-H2
Conjugate: PE
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b κ
Antigen:
CD275
Classification:
Monoclonal
Concentration:
__
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human B7-H2
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
2D3/B7-H2
Conjugate:
PE
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b κ
Antigen: CD126
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mixture of U266, XG-1and BWD41 cells
Quantity: 0.5 mg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: ELISA
Clone: M182
Conjugate: Biotin
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD126
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mixture of U266, XG-1and BWD41 cells
Quantity:
0.5 mg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
ELISA
Clone:
M182
Conjugate:
Biotin
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ