BDB552825

NK T Cell, Invariant Mouse anti-Human, PE, Clone: 6B11, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB552825-Each-of-1 In Stock ₹ 29,903.22

BDB552825 - Each of 1

₹ 29,903.22

In Stock

Quantity

1

Base Price: ₹ 29,903.22

GST (18%): ₹ 5,382.58

Total Price: ₹ 35,285.80

Antigen

NK T Cell, Invariant

Classification

Monoclonal

Conjugate

PE

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

6B11

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Peptide from CDR3 loop of the invariant TCR V24 sequence

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

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Description

  • Monoclonal antibody 6B11 reacts with a unique determinant in the CDR3 region of the invariant (Vα24-JαQ) TCR chain
  • Thus 6B11 identifies a subset of all Vα24 positive T cells
  • The binding of the PE-conjugate of 6B11 can be partially blocked by other antibodies specific for Vα24 (BD Biosciences Pharmingen, data not shown)
  • This invariant chain is expressed on invariant NK T cells, which are a small subset of T lymphocytes that also express other NK cell molecules such as CD161
  • Invariant NK T cells have been reported to play an immunoregulatory role
  • The Vα24-JαQ interacts with the CD1d protein
  • Invariant NK T cells can be specifically activated by CD1d-presented antigen resulting in rapid production of IL-4 and IFN (also known as IFN-γ)
  • Studies of NK T cells describe their role in anti-tumor immunity and autoimmunity
  • This antibody is routinely tested by flow cytometric analysis
  • Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature
  • Host Species: Mouse Clone: 6B11 Isotype: IgG1 κ Species Reactivity: Human Flow Cytometry

Compare Similar Items

Show Difference

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Antigen:
NK T Cell, Invariant

Classification:
Monoclonal

Conjugate:
PE

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
6B11

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Peptide from CDR3 loop of the invariant TCR V24 sequence

Quantity:
100 Tests

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ

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Conjugate:
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Host Species:
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Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Applications:
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Clone:
MAB13

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
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Host Species:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
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Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

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IgG1 κ

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Classification:
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Conjugate:
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Host Species:
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Purification Method:
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Regulatory Status:
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Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
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Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
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Quantity:
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Research Discipline:
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Target Species:
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