BDB552954

CDw93 (C1qRp) Mouse anti-Human, NA/LE, Unlabeled, Clone: R139, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB552954-Each-of-1 In Stock ₹ 44,148.96

BDB552954 - Each of 1

₹ 44,148.96

In Stock

Quantity

1

Base Price: ₹ 44,148.96

GST (18%): ₹ 7,946.813

Total Price: ₹ 52,095.773

Antigen

CDw93 (C1qRp)

Classification

Monoclonal

Concentration

1.0mg/mL

Description

C1qRp

Host Species

Mouse

Quantity

0.5 mg

Research Discipline

Cell Biology

Target Species

Human

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

R139

Conjugate

Unconjugated

Formulation

No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

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Description

  • The immunogen used to raise R139 antibody was C1q-binding protein preparation derived from U937 cell lysates, as described
  • Human CDw93 (C1qRp) is a 631 AA, single chain type I membrane glycoprotein expressed on cells of myeloid origin, endothelial cells, and hematopoietic progenitor cells
  • Human, murine and rat protein sequences have been deduced from cDNA clones and are known to be similar in sequence and organization
  • CDw93 (C1qRp) binds C1q, the recognition subunit of the first component (C1) of the complement pathway, as well as MBL (Mannose-binding-lectin) and SPA (Pulmonary Surfactant Protein A)
  • Multivalent interaction of CDw93 (C1qRp) expressing cells with C1q, MBL, and SPA, induces enhancement of phagocytosis of suboptimally opsonized particles and/or cellular debris
  • Antibody R139 neutralizes/blocks C1q-mediated enhancement of phagocytosis, as reported
  • In addition clone R139 is suitable to detect CDw93 (C1qRp) expression on cells by flow cytometry, CDw93 (C1qRp) in cellular lysates by Western blotting or immunoprecipitation
  • CDw93 (C1qRp) has been reported to define a human stem cell population with hematopoietic and hepatic potential.

Compare Similar Items

Show Difference

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BD Biosciences

BDB552954

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Antigen:
CDw93 (C1qRp)

Classification:
Monoclonal

Concentration:
1.0mg/mL

Description:
C1qRp

Host Species:
Mouse

Quantity:
0.5 mg

Research Discipline:
Cell Biology

Target Species:
Human

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
R139

Conjugate:
Unconjugated

Formulation:
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

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BDB552957

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Antigen:
CD21/CD35

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
CR2/CR1

Host Species:
Rat

Quantity:
0.2 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
7G6

Conjugate:
PE

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
F4/80-Like Receptor

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
Fire; Emr4; EGF-like module receptor 4; D17Ertd479e; Egf-tm7

Host Species:
Rat

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
6F12

Conjugate:
Unconjugated

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

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Antigen:
Ly-6G and Ly-6C

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Ly6c, Lymphocyte antigen 6C2; Lymphocyte antigen 6G, Ly6g, Gr-1

Host Species:
Rat

Quantity:
20 μg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
RB6-8C5

Conjugate:
PE-Cyanine7

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.