BDB553108

Ly-6A/E Rat anti-Mouse, PE, Clone: D7, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB553108-Each-of-1 In Stock ₹ 29,560.98

BDB553108 - Each of 1

₹ 29,560.98

In Stock

Quantity

1

Base Price: ₹ 29,560.98

GST (18%): ₹ 5,320.976

Total Price: ₹ 34,881.956

Antigen

Ly-6A/E

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Ly-6A/E; Lymphocyte antigen 6A-2/6E-1; Ly-6A.2/Ly-6E.1; Sca-1; TAP

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

D7

Conjugate

PE

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

IL-2-dependent mouse T-cell line CTL-L

Quantity

0.2 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG2a κ

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Description

  • The D7 antibody reacts with Ly-6A.2 and Ly-6E.1, which are allelic members of the Ly-6 multigene family
  • Sca-1 (Ly6A/E), a phosphatidylinositol-anchored protein of about 18 kDa, is expressed on the multipotent hematopoietic stem cells (HSC) in the bone marrow of mice with both Ly-6 haplotypes
  • In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, C57L, C58, DBA/2, PL, SJL, SWR, 129), Ly-6A/E is also expressed on distinct subpopulations of bone marrow and peripheral B lymphocytes and thymic and peripheral T lymphocytes
  • Strains with the Ly-6.1 haplotype (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have few Ly-6A/E+ resting peripheral lymphocytes, whereas activation of lymphocytes from mice of both Ly-6 haplotypes leads to strong expression of the Sca-1 antigen
  • Studies with the D7 antibody have demonstrated that Ly-6A/E may be involved in the regulation of B and T lymphocyte responses, and it appears to be required for T-cell receptor-mediated T-cell activation
  • Purified E13-161.7 mAb (anti-Ly-6A/E, Cat
  • No
  • 553333) can block binding of FITC-conjugated D7 antibody (Cat
  • No
  • 557405) to mouse splenocytes, but purified mAb D7 is unable to block binding of FITC-conjugated E13-161.7 antibody (Cat
  • No
  • 553335)
  • Anti-Ly-6A/E (Sca-1) mAb may be used in combination with the Mouse Lineage Panel (Cat
  • No
  • 559971) to identify HSC
  • This antibody is routinely tested by flow cytometric analysis
  • Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Compare Similar Items

Show Difference

Img

Fischer Scientific

BDB553108

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Antigen:
Ly-6A/E

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Ly-6A/E; Lymphocyte antigen 6A-2/6E-1; Ly-6A.2/Ly-6E.1; Sca-1; TAP

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
D7

Conjugate:
PE

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
IL-2-dependent mouse T-cell line CTL-L

Quantity:
0.2 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2a κ

Img

BD Biosciences

BDB553109

--


Antigen:
CD2

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
LFA-2; LFA-3 receptor; Ly37; Ly-37; Lymphocyte antigen 37; T11

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Applications:
Flow Cytometry

Clone:
RM2-5

Conjugate:
Unconjugated

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse BALB/c Thymocytes

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2b λ

Img

BD Biosciences

BDB553110

--


Antigen:
CD2

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
LFA-2; LFA-3 receptor; Ly37; Ly-37; Lymphocyte antigen 37; T11

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
RM2-5

Conjugate:
Biotin

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse BALB/c Thymocytes

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2b λ

Img

BD Biosciences

BDB553111

--


Antigen:
CD2

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
LFA-2; LFA-3 receptor; Ly37; Ly-37; Lymphocyte antigen 37; T11

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
RM2-5

Conjugate:
FITC

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse BALB/c Thymocytes

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2b λ