BDB553139
CD23 Rat anti-Mouse, PE, Clone: B3B4, BD
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB553139-Each-of-1 | In Stock | ₹ 30,749.50 |
BDB553139 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,749.50
GST (18%): ₹ 5,534.91
Total Price: ₹ 36,284.41
Antigen
CD23
Classification
Monoclonal
Concentration
0.2mg/mL
Description
FcεRII; Fc-epsilon-RII; Fcer2a; Ly-42; Low-affinity IgE receptor; Fcer2
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
B3B4
Conjugate
PE
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
FcεR isolated from the mouse B hybridoma line O1.2B2
Quantity
0.2 mg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG2a κ
Related Products
Description
- The B3B4 antibody reacts with CD23, the low affinity IgE Fc receptor (FcεRII) expressed on mature resting conventional B lymphocytes, but not on B-1 cells (CD5+ B cells) or T lymphocytes
- It does not react with high-affinity IgE receptors, as demonstrated on mouse mast cell lines
- The regulation of CD23 surface expression on activated B cells appears to be complex, depending upon the mode of activation and the presence of cytokines
- IgE synthesis is negatively regulated by CD23, and CD23 expression is upregulated on splenocytes in the presence of IgE
- CD23 is also upregulated on follicular dendritic cells in the lymph nodes of immunized mice, and a subset of splenic dendritic cells expresses CD23
- The B3B4 antibody abrogates antigen-specific IgE-dependent modulation of immune responses in normal mice
- This monoclonal antibody also blocks IgE binding and eosinophil infiltration in the lung of immunized mice
- Different in vivo results have been obtained when using the intact B3B4 antibody or the F(ab')2 fragments
- B3B4 mAb does not cross-react with rat or human IgE Fc Receptor.
Compare Similar Items
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Antigen: CD23
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: FcεRII; Fc-epsilon-RII; Fcer2a; Ly-42; Low-affinity IgE receptor; Fcer2
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: B3B4
Conjugate: PE
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: FcεR isolated from the mouse B hybridoma line O1.2B2
Quantity: 0.2 mg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2a κ
Antigen:
CD23
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
FcεRII; Fc-epsilon-RII; Fcer2a; Ly-42; Low-affinity IgE receptor; Fcer2
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
B3B4
Conjugate:
PE
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
FcεR isolated from the mouse B hybridoma line O1.2B2
Quantity:
0.2 mg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2a κ
Antigen: CD16/CD32
Classification: Monoclonal
Concentration: 1.0mg/mL
Description: FcγRIII/FcγRII; Fcgr3/Fcgr2
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Flow Cytometry
Clone: 2.4G2
Conjugate: Unconjugated
Formulation: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen: Mouse BALB/c Macrophage J774
Quantity: 0.5 mg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2b κ
Antigen:
CD16/CD32
Classification:
Monoclonal
Concentration:
1.0mg/mL
Description:
FcγRIII/FcγRII; Fcgr3/Fcgr2
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Flow Cytometry
Clone:
2.4G2
Conjugate:
Unconjugated
Formulation:
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen:
Mouse BALB/c Macrophage J774
Quantity:
0.5 mg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2b κ
Antigen: CD16/CD32
Classification: Monoclonal
Concentration: 0.5mg/mL
Description: FcγRIII/FcγRII; Fcgr3/Fcgr2
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Blocking Assay, Flow Cytometry
Clone: 2.4G2
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse BALB/c Macrophage J774 Cell Line
Quantity: 0.1 mg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2b κ
Antigen:
CD16/CD32
Classification:
Monoclonal
Concentration:
0.5mg/mL
Description:
FcγRIII/FcγRII; Fcgr3/Fcgr2
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Blocking Assay, Flow Cytometry
Clone:
2.4G2
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse BALB/c Macrophage J774 Cell Line
Quantity:
0.1 mg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2b κ
Antigen: CD16/CD32
Classification: Monoclonal
Concentration: 0.5mg/mL
Description: FcγRIII/FcγRII; Fcgr3/Fcgr2
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Blocking Assay, Flow Cytometry
Clone: 2.4G2
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse BALB/c Macrophage J774 Cell Line
Quantity: 0.5 mg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2b κ
Antigen:
CD16/CD32
Classification:
Monoclonal
Concentration:
0.5mg/mL
Description:
FcγRIII/FcγRII; Fcgr3/Fcgr2
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Blocking Assay, Flow Cytometry
Clone:
2.4G2
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse BALB/c Macrophage J774 Cell Line
Quantity:
0.5 mg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2b κ