BDB553153

CD49d Rat anti-Mouse, NA/LE, Unlabeled, Clone: R1-2, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB553153-Each-of-1 In Stock ₹ 35,592.96

BDB553153 - Each of 1

₹ 35,592.96

In Stock

Quantity

1

Base Price: ₹ 35,592.96

GST (18%): ₹ 6,406.733

Total Price: ₹ 41,999.693

Antigen

CD49d

Classification

Monoclonal

Concentration

1.0mg/mL

Description

Integrin α4 chain

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

Applications

Flow Cytometry

Clone

R1-2

Conjugate

Unconjugated

Formulation

No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.

Immunogen

AKR/Cum mouse spontaneous T lymphoma line TK1

Quantity

0.5 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG2b κ

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Description

  • The R1-2 antibody reacts with the integrin α;4 chain (CD49d), which is expressed as a heterdimer with either of two β;, β;1 or β;7 (also known as β;p)
  • The α;4β;1 integrin (VLA-4, CD49d/CD29) is expressed on most peripheral lymphocytes, thymocytes, and monocytes; while the α;4β;7 integrin (LPAM-1) is expressed on peripheral lymphocytes, but on only a small subset of thymocytes
  • These integrins mediate a variety of cell-cell and cell-matrix interactions, recognizing the ligands VCAM-1 (CD106) and fibronectin
  • There is evidence that levels of VLA-4 expression regulate the transendothelial migration of T lymphocytes into inflamed tissues
  • Integrin α;4β;7 also preferentially binds to the mucosal vascular addressin, MAdCAM-1
  • The R1-2 antibody blocks some α;4 integrin-mediated binding functions
  • In combination with mAb 9C10 (MFR4.B) (Cat
  • No
  • 553313), binding of VLA-4 expressing cells to VCAM-1 can be almost completely inhibited.

Compare Similar Items

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BD Biosciences

BDB553153

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Antigen:
CD49d

Classification:
Monoclonal

Concentration:
1.0mg/mL

Description:
Integrin α4 chain

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Applications:
Flow Cytometry

Clone:
R1-2

Conjugate:
Unconjugated

Formulation:
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.

Immunogen:
AKR/Cum mouse spontaneous T lymphoma line TK1

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2b κ

Img

BD Biosciences

BDB553159

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Antigen:
Ly-51

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
6C3/BP-1 Antigen

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
6C3

Conjugate:
Biotin

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
C57L mouse Pre-B lymphhoma cell line L1-2

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2a κ

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BD Biosciences

BDB553162

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Antigen:
NK-1.1

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
Klrb1b, CD161b, Nkrp1b; Klrb1c, CD161c, NK1.1, Nkrp1c

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Applications:
Flow Cytometry

Clone:
PK136

Conjugate:
Unconjugated

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse NK-1+ Spleen and Bone Marrow

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2a κ

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BD Biosciences

BDB553163

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Antigen:
NK-1.1

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
Klrb1b, CD161b, Nkrp1b; Klrb1c, CD161c, NK1.1, Nkrp1c

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
PK136

Conjugate:
Biotin

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Mouse NK-1+ Spleen and Bone Marrow

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2a κ