BDB553312
CD11b Rat anti-Mouse, APC, Clone: M1/70, BD
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB553312-Each-of-1 | In Stock | ₹ 23,400.66 |
BDB553312 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 23,400.66
GST (18%): ₹ 4,212.119
Total Price: ₹ 27,612.779
Antigen
CD11b
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Itgam; Integrin alpha-M; Ly-40; Mac-1a; Mac-1 alpha; CR3A; CR-3 alpha chain
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
M1/70
Conjugate
APC
Formulation
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen
C57BL/10 splenic T cells and concanavalin A-activated C57BL/10 splenocytes
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Human, Mouse
Isotype
IgG2b κ
Related Products
Description
- The M1/70 monoclonal antibody specifically binds to CD11b, also known as Integrin alpha M (Itgam or α;M)
- CD11b is a 170-kDa type 1 transmembrane glycoprotein and belongs to the Integrin alpha chain family
- CD11b serves as the alpha chain of the heterodimeric Mac-1 integrin (CD11b/CD18, α;Mβ;2), also known as complement receptor 3 (CR3)
- Mac-1 mediates adhesion to ICAM-1 (CD54), ICAM-2 (CD102), fibrinogen and binding to C3bi
- Mac-1 is expressed at varying levels on granulocytes, macrophages, myeloid-derived dendritic cells, natural killer cells, microglia, and B-1 B lymphocytes
- Mac-1 expression is rapidly up-regulated on neutrophils after activation, in the same time period that CD62L (L-selectin) is shed from the cell surface
- The M1/70 antibody reportedly blocks cell adherence and C3bi binding but does not block cell-mediated lysis
- Cross-reaction of the M1/70 antibody with CD11b expressed on human monocytes, polymorphonuclear leukocytes, and NK cells has been reported.
Compare Similar Items
Show Difference
Antigen: CD11b
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Itgam; Integrin alpha-M; Ly-40; Mac-1a; Mac-1 alpha; CR3A; CR-3 alpha chain
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: M1/70
Conjugate: APC
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: C57BL/10 splenic T cells and concanavalin A-activated C57BL/10 splenocytes
Quantity: 0.1 mg
Research Discipline: Immunology
Target Species: Human, Mouse
Isotype: IgG2b κ
Antigen:
CD11b
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Itgam; Integrin alpha-M; Ly-40; Mac-1a; Mac-1 alpha; CR3A; CR-3 alpha chain
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
M1/70
Conjugate:
APC
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
C57BL/10 splenic T cells and concanavalin A-activated C57BL/10 splenocytes
Quantity:
0.1 mg
Research Discipline:
Immunology
Target Species:
Human, Mouse
Isotype:
IgG2b κ
Antigen: CD49d
Classification: Monoclonal
Concentration: 0.5mg/mL
Description: Integrin α4 chain
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Flow Cytometry
Clone: 9C10 (MRF4.B)
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse (C57BL/6xA/J)F[1] Fetal Liver Mast MC/9
Quantity: 0.5 mg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2a κ
Antigen:
CD49d
Classification:
Monoclonal
Concentration:
0.5mg/mL
Description:
Integrin α4 chain
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Flow Cytometry
Clone:
9C10 (MRF4.B)
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse (C57BL/6xA/J)F[1] Fetal Liver Mast MC/9
Quantity:
0.5 mg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2a κ
Antigen: CD49e
Classification: Monoclonal
Concentration: 1.0mg/mL
Description: Integrin α5 chain
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Flow Cytometry
Clone: 5H10-27
Conjugate: Unconjugated
Formulation: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen: Mouse mast cell line MC/9
Quantity: 0.5 mg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2a κ
Antigen:
CD49e
Classification:
Monoclonal
Concentration:
1.0mg/mL
Description:
Integrin α5 chain
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Flow Cytometry
Clone:
5H10-27
Conjugate:
Unconjugated
Formulation:
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen:
Mouse mast cell line MC/9
Quantity:
0.5 mg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2a κ
Antigen: Mac-3
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: __
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: M3/84
Conjugate: PE
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse C57Bl/6 peritoneal exudate cells
Quantity: 0.2 mg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
Mac-3
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
__
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
M3/84
Conjugate:
PE
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse C57Bl/6 peritoneal exudate cells
Quantity:
0.2 mg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG1 κ