BDB554992

CD28 Mouse anti-Rat, NA/LE, Unlabeled, Clone: JJ316, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB554992-Each-of-1 In Stock ₹ 41,411.04

BDB554992 - Each of 1

₹ 41,411.04

In Stock

Quantity

1

Base Price: ₹ 41,411.04

GST (18%): ₹ 7,453.987

Total Price: ₹ 48,865.027

Antigen

CD28

Classification

Monoclonal

Concentration

1.0mg/mL

Formulation

No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.

Immunogen

Rat Cd28-transfected BALB/c mouse A20J B lymphoma

Quantity

0.5 mg

Research Discipline

Immunology

Target Species

Rat

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

JJ316

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

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Description

  • The JJ316 antibody reacts with CD28 on virtually all T lymphocytes bearing αβT-cell receptors (TCR), on most γδTCR-bearing T cells, and on a subset of NK cells
  • In the thymus, CD28 expression is developmentally regulated during the maturation of αβTCR-bearing T cells
  • CD28 is a costimulatory receptor required for activation of T cells; its ligands include CD80 (B7-1) and CD86 (B7-2)
  • Soluble JJ316 enhances the proliferative responses and IL-2 production by T cells activated by anti-aß-TCR mAb R73 (Cat
  • no
  • 554910)
  • Furthermore, at high concentrations, cross-linked JJ316 mAb stimulates resting CD4+ and CD8+T cells to proliferate, secrete IL-2, express activation markers, and gain CTL activity in the absence of signaling through the TCR
  • In vivo administration of mAb JJ316 results in blastogenic transformation of peripheral CD4+ cells and dramatic lymphocytosis
  • The alternate anti-rat CD28 mAb JJ319 (Cat
  • no
  • 554993) cannot directly activate T cells, although it has in vitro costimulatory activity.

Compare Similar Items

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Img

BD Biosciences

BDB554992

--


Antigen:
CD28

Classification:
Monoclonal

Concentration:
1.0mg/mL

Formulation:
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.

Immunogen:
Rat Cd28-transfected BALB/c mouse A20J B lymphoma

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Rat

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
JJ316

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Img

BD Biosciences

BDB554993

--


Antigen:
CD28

Classification:
Monoclonal

Concentration:
1.0mg/mL

Formulation:
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.

Immunogen:
Rat CD28-transfected cell line

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Rat

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
JJ319

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Img

BD Biosciences

BDB554998

--


Antigen:
CD49b

Classification:
Monoclonal

Concentration:
0.5mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Cultured Rat Glomerular Epithelial

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse, Rat

Isotype:
IgG2 λ

Applications:
Flow Cytometry

Clone:
HA1/29

Conjugate:
Unconjugated

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Img

BD Biosciences

BDB555000

--


Antigen:
CD49a

Classification:
Monoclonal

Concentration:
1.0mg/mL

Formulation:
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.

Immunogen:
Rat Emulsified Lewis Rat Glomeruli Cells

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Rat

Isotype:
IgG2

Applications:
Flow Cytometry

Clone:
HA31/8

Conjugate:
Unconjugated

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C