BDB555947

Cutaneous Lymphocyte Antigen Rat anti-Human, FITC, Clone: HECA-452, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB555947-Each-of-1 In Stock ₹ 27,165.30

BDB555947 - Each of 1

₹ 27,165.30

In Stock

Quantity

1

Base Price: ₹ 27,165.30

GST (18%): ₹ 4,889.754

Total Price: ₹ 32,055.054

Antigen

Cutaneous Lymphocyte Antigen

Classification

Monoclonal

Conjugate

FITC

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Lymphocyte-depleted Stromal Preparation of Tonsil

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Human, Mouse

Isotype

IgM κ

Applications

Flow Cytometry

Clone

HECA-452

Description

CLA; PSGL-1; CD162; P-selectin glycoprotein ligand 1; SELPL; SELPLG

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The HECA-452 monoclonal antibody specifically reacts with Cutaneous Lymphocyte Associated Antigen (CLA), a carbohydrate domain shared by sialyl Lewis[x] (sLe[x]) and sialyl Lewis[a] (sLe[a]) antigens
  • It serves as a ligand for selectins including CD62E (E-selectin; ELAM-1)
  • CLA is expressed on high endothelium and on lymphocytes including most T lymphocytes infiltrating cutaneous sites of inflammation
  • Amongst peripheral blood cells, it is expressed on monocytes and granulocytes and a subset of lymphocytes
  • The HECA-452 antibody is also reportedly crossreactive with the mouse CLA carbohydrate epitope that is transiently expressed by PSGL-1/CD162 on activated T cells
  • A number of studies suggest that CLA plays an important role in supporting leucocyte adhesive interactions and migration into extravascular tissues during inflammation
  • This antibody is routinely tested by flow cytometric analysis
  • Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Compare Similar Items

Show Difference

Img

Fischer Scientific

BDB555947

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Antigen:
Cutaneous Lymphocyte Antigen

Classification:
Monoclonal

Conjugate:
FITC

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Lymphocyte-depleted Stromal Preparation of Tonsil

Quantity:
100 Tests

Research Discipline:
Immunology

Target Species:
Human, Mouse

Isotype:
IgM κ

Applications:
Flow Cytometry

Clone:
HECA-452

Description:
CLA; PSGL-1; CD162; P-selectin glycoprotein ligand 1; SELPL; SELPLG

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB555948

--


Antigen:
CD46

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
__

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
E4.3

Description:
MCP; TLX

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Img

BD Biosciences

BDB555949

--


Antigen:
CD46

Classification:
Monoclonal

Conjugate:
FITC

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
__

Quantity:
100 Tests

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
E4.3

Description:
MCP; TLX

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB555950

--


Antigen:
__

Classification:
__

Conjugate:
Unconjugated

Formulation:
__

Immunogen:
Pooled Mouse Ig

Quantity:
0.1 mg

Research Discipline:
__

Target Species:
__

Isotype:
IgM κ

Applications:
Flow Cytometry

Clone:
R4-22

Description:
__

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
__

Primary or Secondary:
__

Content And Storage:
Undiluted at 4°C