BDB555998
CD221 Mouse anti-Human, Unlabeled, Clone: 1H7, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB555998-Each-of-1 | In Stock | ₹ 14,091.73 |
BDB555998 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 14,091.73
GST (18%): ₹ 2,536.511
Total Price: ₹ 16,628.241
Antigen
CD221
Classification
Monoclonal
Concentration
0.5mg/mL
Description
IGF1R; IGF-I receptor; IGFIR; IGFR; Insulin-like growth factor 1 receptor
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Applications
Flow Cytometry
Clone
1H7
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Purified Human Placental IGF-I Receptor
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Human
Isotype
IgG1 κ
Description
- The 1H7 monoclonal antibody specifically binds to the α subunit of the human insulin-like growth factor-I (IGF-I) receptor that is also known as CD221
- CD221 is a receptor tyrosine kinase that has high affinity for IGF-1 and low affinity for insulin and IGF-2
- CD221 is synthesized as a 180 kDa precursor molecule that is processed into two subunits, a 135 kDa α subunit which is disulfide-linked to a 90 kDa β subunit
- The mature IGF-IR complex is comprised of two extracellular α subunits and two transmembrane β subunits that each possesses a tyrosine kinase domain
- When bound by ligand, the IGF-1 receptor autophosphorylates multiple tyrosine sites in its β chains and phosphorylates other signaling molecules that regulate cell growth, development, and neoplastic transformation
- CD221 is structurally and functionally similar to the insulin receptor (aka, CD220) and is expressed on a variety of human hematopoietic and non-hematopoietic cells
- The 1H7 antibody does not crossreact with the human insulin receptor and can block IGF-I- or IGF-II-stimulated cell growth
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Compare Similar Items
Show Difference
Antigen: CD221
Classification: Monoclonal
Concentration: 0.5mg/mL
Description: IGF1R; IGF-I receptor; IGFIR; IGFR; Insulin-like growth factor 1 receptor
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Flow Cytometry
Clone: 1H7
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Purified Human Placental IGF-I Receptor
Quantity: 0.1 mg
Research Discipline: Immunology
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD221
Classification:
Monoclonal
Concentration:
0.5mg/mL
Description:
IGF1R; IGF-I receptor; IGFIR; IGFR; Insulin-like growth factor 1 receptor
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Flow Cytometry
Clone:
1H7
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Purified Human Placental IGF-I Receptor
Quantity:
0.1 mg
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD221
Classification: Monoclonal
Concentration: __
Description: IGF1R; IGF-I receptor; IGFIR; IGFR; Insulin-like growth factor 1 receptor
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 1H7
Conjugate: PE
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Purified Human Placental IGF-I Receptor
Quantity: 100 Tests
Research Discipline: Immunology
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD221
Classification:
Monoclonal
Concentration:
__
Description:
IGF1R; IGF-I receptor; IGFIR; IGFR; Insulin-like growth factor 1 receptor
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
1H7
Conjugate:
PE
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Purified Human Placental IGF-I Receptor
Quantity:
100 Tests
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD140a
Classification: Monoclonal
Concentration: 0.5mg/mL
Description: PDGF Receptor α; PDGFRA; PDGFRα; PDGF-R-alpha; PDGFR2; PGFRA; RHEPDGFRA
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Flow Cytometry
Clone: AR1
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human PDGFRα Transfected Cell Line
Quantity: 0.1 mg
Research Discipline: Immunology
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD140a
Classification:
Monoclonal
Concentration:
0.5mg/mL
Description:
PDGF Receptor α; PDGFRA; PDGFRα; PDGF-R-alpha; PDGFR2; PGFRA; RHEPDGFRA
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Flow Cytometry
Clone:
AR1
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human PDGFRα Transfected Cell Line
Quantity:
0.1 mg
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG2a κ
Antigen: Ki-67
Classification: Monoclonal
Concentration: 0.5mg/mL
Description: MKI67; Antigen identified by monoclonal antibody Ki-67; KIA
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: In vitro Assay, Flow Cytometry
Clone: B56
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human Ki-67
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human, Mouse, Rat, Rhesus Monkey
Isotype: IgG1 κ
Antigen:
Ki-67
Classification:
Monoclonal
Concentration:
0.5mg/mL
Description:
MKI67; Antigen identified by monoclonal antibody Ki-67; KIA
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
In vitro Assay, Flow Cytometry
Clone:
B56
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human Ki-67
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse, Rat, Rhesus Monkey
Isotype:
IgG1 κ