BDB556079

CD161 Mouse anti-Human, Unlabeled, Clone: DX12, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB556079-Each-of-1 In Stock ₹ 14,031.84

BDB556079 - Each of 1

₹ 14,031.84

In Stock

Quantity

1

Base Price: ₹ 14,031.84

GST (18%): ₹ 2,525.731

Total Price: ₹ 16,557.571

Antigen

CD161

Classification

Monoclonal

Concentration

0.5mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Human NKR-P1A Transfected Mouse Fibroblasts

Quantity

0.1 mg

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

DX12

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

Description

  • The DX12 monoclonal antibody specifically binds to human CD161 which is also known as Natural killer cell surface protein P1A (NKR-P1A)
  • CD161 is encoded by the KLRB1 (Killer cell lectin-like receptor subfamily B member 1) gene
  • CD161 is a member of the C-type lectin superfamily and is also referred to as C-type lectin domain family 5 member B (CLEC5B)
  • CD161 is a 80 kDa disulfide-linked homodimer, type II membrane glycoprotein
  • CD161 is expressed mostly on NK cell populations and on subsets of CD4+ and CD8+ αβ T cells, NKT cells and γδ T cells
  • Reports indicate that CD161 is expressed preferentially on CD45RO+ T cells, however, it can be found on a subset of thymocytes and fetal liver T cells
  • Its function has not been fully elucidated, but reports indicate that NKR-P1A may serve as a specific receptor for some NK cell targets
  • The DX12 antibody can reportedly inhibit spontaneous cytotoxicity mediated by certain NK cell clones.

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Antigen:
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Classification:
Monoclonal

Concentration:
0.5mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Human NKR-P1A Transfected Mouse Fibroblasts

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
DX12

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

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CD161

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Monoclonal

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Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human NKR-P1A Transfected Mouse Fibroblasts

Quantity:
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Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
DX12

Conjugate:
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Host Species:
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Purification Method:
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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
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Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human NKR-P1A Transfected Mouse Fibroblasts

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Research Discipline:
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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
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Concentration:
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Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

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Target Species:
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Isotype:
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