BDB557001

P-glycoprotein Mouse anti-Human, Unlabeled, Clone: 17F9, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB557001-Each-of-1 In Stock ₹ 23,614.56

BDB557001 - Each of 1

₹ 23,614.56

In Stock

Quantity

1

Base Price: ₹ 23,614.56

GST (18%): ₹ 4,250.621

Total Price: ₹ 27,865.181

Antigen

P-glycoprotein

Classification

Monoclonal

Concentration

0.5mg/mL

Description

CD243; ABCB1; ABC20; CLCS; GP170; MDR1; P-GP; PGY1

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

Applications

Flow Cytometry

Clone

17F9

Conjugate

Unconjugated

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Human MDR1 Transfected Cell Line

Quantity

0.1 mg

Research Discipline

Cell Biology

Target Species

Human

Isotype

IgG2b κ

Description

  • Reacts with a 170-180kDa transmembrane glycoprotein (P-glycoprotein), a product of the multidrug resistance-1 (MDR1) gene
  • This glycoprotein is expressed on MDR positive cells and has been reported to be expressed on many normal tissues, such as adrenal glands and endothelium, in the brain and skin
  • P-glycoprotein is known to impart drug resistance to cells by pumping many anti-cancer drugs out of the cytoplasm
  • 17F9 antibody binds to the surface of the viable, unfixed MDR+ cell line, PMG-Y (please inquire), and is able to partially block the binding of UIC2 antibody (another MDR-specific monoclonal antibody)
  • Immunoprecipitation application is reported, but not routinely tested in house
  • Host Species: Mouse Clone: 17F9 Isotype: IgG2b, κ Cross Reactivity: Human Flow Cytometry, Immunoprecipitation, Western Blotting

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Antigen:
P-glycoprotein

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
CD243; ABCB1; ABC20; CLCS; GP170; MDR1; P-GP; PGY1

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Applications:
Flow Cytometry

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17F9

Conjugate:
Unconjugated

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Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Human MDR1 Transfected Cell Line

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0.1 mg

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Cell Biology

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Human

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IgG2b κ

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Description:
CD243; ABCB1; ABC20; CLCS; GP170; MDR1; P-GP; PGY1

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Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
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PE

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