BDB557045
MGMT Mouse anti-Human, Unlabeled, Clone: MT5.1, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB557045-Each-of-1 | In Stock | ₹ 29,904.00 |
BDB557045 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,904.00
GST (18%): ₹ 5,382.72
Total Price: ₹ 35,286.72
Antigen
MGMT
Classification
Monoclonal
Concentration
0.5mg/mL
Description
Methylguanine-DNA Methyltransferase
Host Species
Mouse
Quantity
0.1 mg
Research Discipline
Cell Biology
Target Species
Human
Isotype
IgG1 κ
Applications
Western Blot
Clone
MT5.1
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Description
- The repair of mismatched DNA is essential to maintaining the integrity of genetic information over time
- The important role played by DNA repair enzymes is emphasized by the fact that they are highly conserved from bacteria to yeast to mammals
- In bacteria, DNA repair involves the activity of repair enzymes including the MutL, MutH, and MutS proteins, as well as an enzyme originally identified in bacteria, and subsequently in all mammalian species, MGMT (methylguanine-DNA methyltransferase)
- Human MGMT is a 21kDa protein which protects cells from the mutagenic effect of alkylating agents, which add a methyl group to the O6 position of guanine in DNA, producing O6-methylguanine
- While MGMT is generally ubiquitously expressed in mammalian cells, the expression levels within cell and tissue types can be quite variable
- Certain tumor cell types have been identified which express neither MGMT protein or mRNA, despite the apparent normal expression of the MGMT gene
- The variable expression of MGMT may be a factor in the susceptibility of cells and tissues to the mutagenic effects of alkylating agents
- It has been suggested that methylation of cytosine in the MGMT gene and promoter region may correlate with the expression of the MGMT gene product
- MGMT is observed at 21kDa on SDS-PAGE
- Host Species: Mouse Clone: MT5.1 Isotype: IgG1 Cross Reactivity: Human Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blotting
Compare Similar Items
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Antigen: MGMT
Classification: Monoclonal
Concentration: 0.5mg/mL
Description: Methylguanine-DNA Methyltransferase
Host Species: Mouse
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1 κ
Applications: Western Blot
Clone: MT5.1
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
MGMT
Classification:
Monoclonal
Concentration:
0.5mg/mL
Description:
Methylguanine-DNA Methyltransferase
Host Species:
Mouse
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
MT5.1
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: CD69
Classification: Monoclonal
Concentration: __
Description: AIM; CLEC2C; EA1; GP32/28; Leu23; MLR-3; VEA; BL-AC/P26
Host Species: Mouse
Quantity: 50 Tests
Research Discipline: Immunology
Target Species: Baboon, Cynomolgus, Rhesus Monkey
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: FN50
Conjugate: PE
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD69
Classification:
Monoclonal
Concentration:
__
Description:
AIM; CLEC2C; EA1; GP32/28; Leu23; MLR-3; VEA; BL-AC/P26
Host Species:
Mouse
Quantity:
50 Tests
Research Discipline:
Immunology
Target Species:
Baboon, Cynomolgus, Rhesus Monkey
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
FN50
Conjugate:
PE
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD3
Classification: Monoclonal
Concentration: 1.0mg/mL
Description: __
Host Species: Mouse
Quantity: 0.5 mg
Research Discipline: Immunology
Target Species: Baboon, Cynomolgus, Rhesus Monkey
Isotype: IgG3 λ
Applications: Flow Cytometry
Clone: SP34
Conjugate: Unconjugated
Formulation: No azide/low endotoxin: Aqueous buffered solution containing protein stabilizer, no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
CD3
Classification:
Monoclonal
Concentration:
1.0mg/mL
Description:
__
Host Species:
Mouse
Quantity:
0.5 mg
Research Discipline:
Immunology
Target Species:
Baboon, Cynomolgus, Rhesus Monkey
Isotype:
IgG3 λ
Applications:
Flow Cytometry
Clone:
SP34
Conjugate:
Unconjugated
Formulation:
No azide/low endotoxin: Aqueous buffered solution containing protein stabilizer, no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: IFN-g
Classification: Monoclonal
Concentration: __
Description: __
Host Species: Mouse
Quantity: 50 Tests
Research Discipline: Immunology
Target Species: Baboon, Cynomolgus, Rhesus Monkey
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: 4S.B3
Conjugate: PE
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
IFN-g
Classification:
Monoclonal
Concentration:
__
Description:
__
Host Species:
Mouse
Quantity:
50 Tests
Research Discipline:
Immunology
Target Species:
Baboon, Cynomolgus, Rhesus Monkey
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
4S.B3
Conjugate:
PE
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.