BDB557695

CD4 Mouse anti-Human, Alexa Fluor 488, Clone: RPA-T4, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB557695-Each-of-1 In Stock ₹ 30,929.94

BDB557695 - Each of 1

₹ 30,929.94

In Stock

Quantity

1

Base Price: ₹ 30,929.94

GST (18%): ₹ 5,567.389

Total Price: ₹ 36,497.329

Antigen

CD4

Classification

Monoclonal

Conjugate

Alexa Fluor 488

Host Species

Mouse

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

RPA-T4

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • The RPA-T4 monoclonal antibody specifically binds to CD4, a 59 kDa single-chain transmembrane glycoprotein that is expressed on T-helper/inducer cell populations
  • CD4 is also expressed on thymocytes subsets and at lower levels on monocytes and macrophages
  • CD4 functions as a co-receptor in MHC class II-restricted antigen-induced T cell activation and as a receptor for human immunodeficiency viruses (HIV)
  • This antibody binds to the D1 domain (CDR1 and CDR3 epitopes) of the CD4 antigen and reacts with approximately 80% of thymocytes and 45% of peripheral blood lymphocytes
  • RPA-T4 is capable of blocking HIV-1, gp120, and inhibits syncytium formation.

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