BDB557834

CD8 Mouse anti-Human, APC-Cy7, Clone: SK1, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB557834-Each-of-1 In Stock ₹ 31,956.66

BDB557834 - Each of 1

₹ 31,956.66

In Stock

Quantity

1

Base Price: ₹ 31,956.66

GST (18%): ₹ 5,752.199

Total Price: ₹ 37,708.859

Antigen

CD8

Classification

Monoclonal

Conjugate

APC-Cyanine7

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human Peripheral Blood T Cells

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

SK1

Description

CD8α; CD8A; CD8 alpha; Leu2a; MAL; T8; p32

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The SK1 monoclonal antibody specifically binds to CD8 alpha (CD8α)
  • CD8α is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily
  • CD8α is expressed by the majority of thymocytes, by subpopulations of αβ T cells and γδ T cells and by some NK cells
  • Cell surface CD8α is expressed either as a disulfide-linked homodimer (CD8αα) or as a heterodimer (CD8αβ) when disulfide-bonded to a CD8 beta chain (CD8β)
  • CD8-positive αβ T cells coexpress both CD8αα homodimers and CD8αβ heterodimers whereas some γδ T cells and NK cells express CD8αα homodimers
  • CD8 plays important roles in T cell activation and selection
  • The extracellular IgSF domain of CD8α binds to a non-polymorphic determinant on HLA class I molecules (α3 domain) and enables CD8 to function as a co-receptor with MHC class I-restricted TCR during T cell recognition of antigen
  • The cytoplasmic domain of CD8α associates with Lck, a Src family protein tyrosine kinase that is involved in intracellular signaling.

Compare Similar Items

Show Difference

Img

Fischer Scientific

BDB557834

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Antigen:
CD8

Classification:
Monoclonal

Conjugate:
APC-Cyanine7

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human Peripheral Blood T Cells

Quantity:
100 Tests

Research Discipline:
Immunology

Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
SK1

Description:
CD8α; CD8A; CD8 alpha; Leu2a; MAL; T8; p32

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

BD Biosciences

BDB557844

--


Antigen:
IFN-g

Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Human IFN-γ from supernatants of S. aureus-stimulated PBMC

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
4S.B3

Description:
__

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

Fischer Scientific

BDB557847

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Antigen:
NKp46

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.

Immunogen:
Human NKp46 Recombinant Protein

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
9E2/NKP46

Description:
__

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

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BD Biosciences

BDB557851

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Antigen:
CD3

Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human Thymocytes

Quantity:
100 Tests

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
SK7

Description:
CD3-epsilon; CD3E; Leu4; T-cell surface antigen T3/Leu-4 epsilon chain; T3E

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.