BDB557860

CD279 Mouse anti-Human, FITC, Clone: MIH4, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB557860-Each-of-1 In Stock ₹ 25,282.98

BDB557860 - Each of 1

₹ 25,282.98

In Stock

Quantity

1

Base Price: ₹ 25,282.98

GST (18%): ₹ 4,550.936

Total Price: ₹ 29,833.916

Antigen

CD279

Classification

Monoclonal

Concentration

0.5mg/mL

Description

PD-1; hPD-1; PD1; PDCD1; Programmed cell death 1; SLEB2

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

MIH4

Conjugate

FITC

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Human PD-1 Transfected Cell Line

Quantity

0.1 mg

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

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Description

  • The MIH4 monoclonal antibody specifically binds to the program death 1 (PD-1) receptor CD279, a member of the Ig superfamily
  • CD279 is an immunoregulatory receptor expressed on activated T cells, B cells and myeloid cells
  • Mice deficient in CD279 show a breakdown of peripheral tolerance and manifest multiple autoimmune symptoms
  • It contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region
  • PD-L1 and PD-L2 are ligands of CD279 and are members of the B7 gene family
  • Interaction of CD279:PD-Ligands results in inhibition of T cell proliferation and cytokine secretion
  • Reports suggest that the B7/CTLA-4 pathway functions primarily to attenuate, limit, and/or terminate naοve T-cell activation in secondary lymphoid organs
  • The PD-ligand:CD279 pathway, on the other hand, may primarily attenuate, limit, and/or terminate T-, B-, and myeloid cell activation/effector function at sites of inflammation in the periphery.

Compare Similar Items

Show Difference

Img

Fischer Scientific

BDB557860

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Antigen:
CD279

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
PD-1; hPD-1; PD1; PDCD1; Programmed cell death 1; SLEB2

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
MIH4

Conjugate:
FITC

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Human PD-1 Transfected Cell Line

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB557863

--


Antigen:
CD194

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
CCR4; C-C chemokine receptor type 4; CMKBR4; K5-5

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
1G1

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Human CCR4 Transfected Cell Line

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ

Img

Fischer Scientific

BDB557864

--


Antigen:
CD194

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
CCR4; C-C chemokine receptor type 4; CMKBR4; K5-5

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
1G1

Conjugate:
PE-Cyanine7

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Human CCR4 Transfected Cell Line

Quantity:
0.1 mg

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ

Img

Fischer Scientific

BDB557865

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Antigen:
__

Classification:
__

Concentration:
__

Description:
__

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
__

Primary or Secondary:
__

Content And Storage:
Undiluted at 4°C

Applications:
Flow Cytometry, Western Blot

Clone:
R3-34

Conjugate:
Alexa Fluor 647

Formulation:
__

Immunogen:
__

Quantity:
100 Tests

Research Discipline:
__

Target Species:
__

Isotype:
IgG1 κ