BDB558034
Btk (pY551) and Itk (pY511) Mouse, Unlabeled, Clone: 24A/BTK (Y551), BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB558034-Each-of-1 | In Stock | ₹ 52,063.26 |
BDB558034 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,063.26
GST (18%): ₹ 9,371.387
Total Price: ₹ 61,434.647
Antigen
Btk (pY551) and Itk (pY511)
Classification
Monoclonal
Concentration
0.5mg/mL
Description
ATK; BPK; AGMX1
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Isotype
IgG1 κ
Applications
Western Blot
Clone
24A/BTK (Y551)
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Phosphorylated Human Btk Peptide
Quantity
0.1 mg
Research Discipline
Cell Biology
Content And Storage
Store undiluted at 4°C
Description
- B ruton's t yrosine k inase (Btk) is a nonreceptor tyrosine kinase whose function is critical for proper B cell development and signaling
- The activity of Btk is regulated by Src mediated phosphorylation of the kinase domain at tyrosine 551 (Y551)
- This event induces Btk kinase activity and subsequent autophosphorylation at Y223
- Phosphorylated Btk then associates with the cell membrane via the interaction of the PH domain with phosphatidylinositol 3, 4, 5-triphosphate
- γ1 (PLC γ1), a key regulator of calcium mobilization and extracellular signal-regulated kinase (ERK) activation
- Itk is regulated by an activating transphosphorylation event in which Y511 in the kinase domain is phosphorylated by Lck
- The 24a/BTK (Y551) monoclonal antibody recognizes the Y551-phosphorylated form of human Btk and the Y511 phosphorylated form of human Itk.
Compare Similar Items
Show Difference
Antigen: Btk (pY551) and Itk (pY511)
Classification: Monoclonal
Concentration: 0.5mg/mL
Description: ATK; BPK; AGMX1
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Isotype: IgG1 κ
Applications: Western Blot
Clone: 24A/BTK (Y551)
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Phosphorylated Human Btk Peptide
Quantity: 0.1 mg
Research Discipline: Cell Biology
Content And Storage: Store undiluted at 4°C
Antigen:
Btk (pY551) and Itk (pY511)
Classification:
Monoclonal
Concentration:
0.5mg/mL
Description:
ATK; BPK; AGMX1
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
24A/BTK (Y551)
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human Btk Peptide
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Content And Storage:
Store undiluted at 4°C
Antigen: c-Cbl (pY774)
Classification: Monoclonal
Concentration: 0.5mg/mL
Description: __
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Isotype: IgG1 κ
Applications: Western Blot
Clone: 29/C-CBL
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Phosphorylated Human c-Cbl Peptide
Quantity: 0.1 mg
Research Discipline: Cell Biology
Content And Storage: Store undiluted at 4°C
Antigen:
c-Cbl (pY774)
Classification:
Monoclonal
Concentration:
0.5mg/mL
Description:
__
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
29/C-CBL
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human c-Cbl Peptide
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Content And Storage:
Store undiluted at 4°C
Antigen: c-Jun (pS63)
Classification: Monoclonal
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Description: __
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
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Clone: 2/C-JUN (PS63)
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
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Research Discipline: Cell Biology
Content And Storage: Store undiluted at -20°C.
Antigen:
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Concentration:
0.25mg/mL
Description:
__
Host Species:
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Purification Method:
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Regulatory Status:
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Primary or Secondary:
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Isotype:
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Applications:
Western Blot
Clone:
2/C-JUN (PS63)
Conjugate:
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Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human c-Jun
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Content And Storage:
Store undiluted at -20°C.
Antigen: CD55
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: DAF, decay-accelerating factor
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Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Isotype: IgG3 λ
Applications: Flow Cytometry
Clone: RIKO-5
Conjugate: PE
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: __
Quantity: 0.1 mg
Research Discipline: __
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD55
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
DAF, decay-accelerating factor
Host Species:
Hamster
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Isotype:
IgG3 λ
Applications:
Flow Cytometry
Clone:
RIKO-5
Conjugate:
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Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
__
Quantity:
0.1 mg
Research Discipline:
__
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.