BDB558394
Tyk2 (pY1054/pY1055) Mouse anti-Human, Unlabeled, Clone: I114-617, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB558394-Each-of-1 | In Stock | ₹ 51,849.36 |
BDB558394 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,849.36
GST (18%): ₹ 9,332.885
Total Price: ₹ 61,182.245
Antigen
Tyk2 (pY1054/pY1055)
Classification
Monoclonal
Concentration
0.5mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Phosphorylated peptide of the region including the tyrosines 1054 and 1055 of human Tyk2
Quantity
0.1 mg
Research Discipline
Cell Biology
Target Species
Human
Isotype
IgG1 κ
Applications
Western Blot
Clone
I114-617
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Description
- Tyk2 is a widely expressed protein tyrosine kinase (PTK) of 1187 amino acids (135kDa)
- The N-terminal kinase-related domain of Tyk2 shows 54% identity to the kinase-related domain of the JAK1 kinase
- Surprisingly, the catalytic region of JAK1 shares more sequence identity to Tyk2 than it does with JAK2 kinase
- The similarity of structure between Tyk2 and JAK1 suggests that both may be involved in related phosphorylation cascades
- Tyk2 plays a critical role in the interferon (IFN)-a/b response while JAK1 shows involvement in both the IFN- α/β and IFN-γ signal transduction pathways
- JAK2, however, appears to be required only in the IFN-g response
- It has been suggested that a portion of the large extracatalytic domain of Tyk2 could interact with components of the IFN a/b receptor
- The I114-617 monoclonal antibody recognizes the phosphorylated Y1054 and Y1055 in the tyrosine kinase domain of Tyk2
- Western Blotting
Compare Similar Items
Show Difference
Antigen: Tyk2 (pY1054/pY1055)
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Phosphorylated peptide of the region including the tyrosines 1054 and 1055 of human Tyk2
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1 κ
Applications: Western Blot
Clone: I114-617
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
Tyk2 (pY1054/pY1055)
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Phosphorylated peptide of the region including the tyrosines 1054 and 1055 of human Tyk2
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
I114-617
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: PDPK1 (pS241)
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Phosphorylated Human PDPK1 Peptide
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human, Mouse, Rat
Isotype: IgG1 κ
Applications: Western Blot
Clone: J66-653.44.22
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
PDPK1 (pS241)
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human PDPK1 Peptide
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse, Rat
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
J66-653.44.22
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: TBK1 (pS172)
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Phosphorylated Human TBK1
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgG2b κ
Applications: Western Blot
Clone: J133-1171
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
TBK1 (pS172)
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human TBK1
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgG2b κ
Applications:
Western Blot
Clone:
J133-1171
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: PLK1 (pT210)
Classification: Monoclonal
Concentration: 0.5mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Phosphorylated Human PLK1 Peptide
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgG1 κ
Applications: Western Blot
Clone: K50-483
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
PLK1 (pT210)
Classification:
Monoclonal
Concentration:
0.5mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human PLK1 Peptide
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
K50-483
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C