BDB558403
CD314 Rat anti-Mouse, PE, Clone: CX5, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB558403-Each-of-1 | In Stock | ₹ 31,443.30 |
BDB558403 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,443.30
GST (18%): ₹ 5,659.794
Total Price: ₹ 37,103.094
Antigen
CD314
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Klrk1; NKG2D; NKG2-D; NK cell receptor D; Natural killer cell group 2D
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
CX5
Conjugate
PE
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Mouse NKG2D protein
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG1
Description
- The CX5 monoclonal antibody specifically binds to NKG2D, also known as CD314
- NKG2D is a lectin-like receptor that is detected on resting and IL-2-activated NK cells, activated CD8-positive T lymphocytes, and LPS-activated macrophages, but not on resting T cells or unstimulated macrophages
- NKG2D has little homology to the other members of the NKG2 family, NKG2A, C, and E, and does not form heterodimers with CD94
- On NK cells, NKG2D is an activating receptor that associates with DAP10, an adapter protein that stimulates the PI3 kinase pathway
- An isoform of mouse NKG2D can also associate with the signaling adapter protein DAP12, also known as KARAP ( K iller cell- A ssociated R eceptor- olypeptide), that activates the Syk and ZAP70 tyrosine kinases
- On cytotoxic T cells, NKG2D is a co-stimulatory receptor that associates with DAP10
- The ligands for NKG2D include the minor histocompatibility antigen H60, MULT1 ( M urine UL 16-binding protein- L ike T ranscript ), and the five retinoic acid-inducible proteins Rae-1 a , b , g , d and e
- Interactions of NKG2D with its ligands are involved in the regulation of innate and immune cytotoxic responses to tumor and pathogen-infected cells and in diabetes progression in the NOD mouse
- The CX5 mAb blocks the binding of NKG2D to its ligands.
Compare Similar Items
Show Difference
Antigen: CD314
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Klrk1; NKG2D; NKG2-D; NK cell receptor D; Natural killer cell group 2D
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: CX5
Conjugate: PE
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse NKG2D protein
Quantity: 0.1 mg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG1
Antigen:
CD314
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Klrk1; NKG2D; NKG2-D; NK cell receptor D; Natural killer cell group 2D
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
CX5
Conjugate:
PE
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse NKG2D protein
Quantity:
0.1 mg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG1
Antigen: CD192
Classification: Monoclonal
Concentration: __
Description: CCR2; MCP-1-R; CC-CKR-2; CMKBR2; CKR2; CCR2A; CCR2B; CKR2A; CKR2B
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 48607
Conjugate: Alexa Fluor 647
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human hCCR2-transfected NS0
Quantity: 100 Tests
Research Discipline: Immunology
Target Species: Human
Isotype: IgG2b
Antigen:
CD192
Classification:
Monoclonal
Concentration:
__
Description:
CCR2; MCP-1-R; CC-CKR-2; CMKBR2; CKR2; CCR2A; CCR2B; CKR2A; CKR2B
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
48607
Conjugate:
Alexa Fluor 647
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human hCCR2-transfected NS0
Quantity:
100 Tests
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG2b
Antigen: CD337
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: NCR3; Natural cytotoxicity triggering receptor 3; NKp30; MALS; LY117; 1C7
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: P30-15
Conjugate: PE
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human NKp30 e tracellular domain Transfected Cell Line
Quantity: 0.1 mg
Research Discipline: Immunology
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD337
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
NCR3; Natural cytotoxicity triggering receptor 3; NKp30; MALS; LY117; 1C7
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
P30-15
Conjugate:
PE
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human NKp30 e tracellular domain Transfected Cell Line
Quantity:
0.1 mg
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD337
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: __
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: P30-15
Conjugate: Alexa Fluor 647
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: Human NKp30 e tracellular domain
Quantity: 0.1 mg
Research Discipline: Immunology
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD337
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
__
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
P30-15
Conjugate:
Alexa Fluor 647
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
Human NKp30 e tracellular domain
Quantity:
0.1 mg
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG1 κ