BDB558490
PLC-γ2 (pY759) Mouse, PE, Clone: K86-689.37, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB558490-Each-of-1 | In Stock | ₹ 27,165.30 |
BDB558490 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 27,165.30
GST (18%): ₹ 4,889.754
Total Price: ₹ 32,055.054
Antigen
PLC-γ2 (pY759)
Classification
Monoclonal
Conjugate
PE
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
K86-689.37
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Phosphorylated Human PLC-γ2 Peptide
Quantity
50 Tests
Research Discipline
Cell Biology
Target Species
Human, Mouse, Rat
Isotype
IgG1 κ
Description
- Description The Phospholipase C (PLC) isozymes hydrolyze phosphatidyl inositol biphosphate to inositol triphosphate and diacylglycerol
- The former causes release of calcium from the endoplasmic reticulum, while the latter is an activator of Protein Kinase C
- Within the PLC family, PLC-γ is the only member that contains SH2 and SH3 domains
- These domains enable it to interact with protein tyrosine kinases and become enzymatically activated via phosphorylation
- It exists as two isoforms: PLC-γ1, which is ubiquitously expressed, and PLC-γ2, which is found primarily in the hematopoietic system
- PLC-γ2-null mice exhibit impaired B lymphocyte maturation and defects in Fc receptor functions
- Phosphorylation of PLC-γ2 at tyrosines 753 and 759 (Y759) is required for activation of PLC-γ2 enzyme activity
- PLC-γ2 phosphorylation at Y759 can be induced by stimulation of the B cell receptor in Ramos cell, the collagen receptor in platelets, and the T cell receptor in Jurkat cells, and it occurs downstream of Btk and BLNK in the signaling cascade of activated B cells
- The K86-689.37.73 antibody recognizes PLC-γ2 phosphorylated at Y759 in the SH2-SH3 linker region
- Intracellular Staining
Compare Similar Items
Show Difference
Antigen: PLC-γ2 (pY759)
Classification: Monoclonal
Conjugate: PE
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: K86-689.37
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Phosphorylated Human PLC-γ2 Peptide
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Human, Mouse, Rat
Isotype: IgG1 κ
Antigen:
PLC-γ2 (pY759)
Classification:
Monoclonal
Conjugate:
PE
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
K86-689.37
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human PLC-γ2 Peptide
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Human, Mouse, Rat
Isotype:
IgG1 κ
Antigen: Rat T Lymphocyte Cocktail
Classification: Monoclonal
Conjugate: FITC/APC/PE
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 1F4, OX-35, OX-8
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: __
Quantity: 50 Tests
Research Discipline: __
Target Species: __
Isotype: IgM
Antigen:
Rat T Lymphocyte Cocktail
Classification:
Monoclonal
Conjugate:
FITC/APC/PE
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
1F4, OX-35, OX-8
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
__
Quantity:
50 Tests
Research Discipline:
__
Target Species:
__
Isotype:
IgM
Antigen: __
Classification: __
Conjugate: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Content And Storage: __
Applications: __
Clone: __
Formulation: __
Immunogen: __
Quantity: __
Research Discipline: __
Target Species: __
Isotype: __
Antigen:
__
Classification:
__
Conjugate:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Content And Storage:
__
Applications:
__
Clone:
__
Formulation:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Target Species:
__
Isotype:
__
Antigen: Lck
Classification: Monoclonal
Conjugate: PE
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: MOL 171
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human N-terminal Lck Peptide
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgG1 κ
Antigen:
Lck
Classification:
Monoclonal
Conjugate:
PE
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
MOL 171
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human N-terminal Lck Peptide
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgG1 κ