BDB558588

CD221 (pY1131) Mouse, Alexa Fluor 647, Clone: K74-218, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB558588-Each-of-1 In Stock ₹ 27,165.30

BDB558588 - Each of 1

₹ 27,165.30

In Stock

Quantity

1

Base Price: ₹ 27,165.30

GST (18%): ₹ 4,889.754

Total Price: ₹ 32,055.054

Antigen

CD221 (pY1131)

Classification

Monoclonal

Conjugate

Alexa Fluor 647

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Phosphorylated Human IGF-1 Receptor Peptide

Quantity

50 Tests

Research Discipline

Cell Biology

Target Species

Human, Mouse, Rat

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

K74-218

Description

IGF1R; IGF-I receptor; IGFIR; IGFR; Insulin-like growth factor 1 receptor

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • Insulin-like growth factor-1 (IGF-1) receptor, or CD221, is a receptor tyrosine kinase that has high affinity for IGF-1 and low affinity for insulin and IGF-2
  • Each transmembrane protein complex is formed from a pair of 1367 amino-acid precursor proteins
  • After the 30 amino-acid signal sequences are removed, the paired polypeptides are cleaved to derive an a and b chain from each
  • The two extracellular a chains form the ligand-binding domain, while the transmembrane-and-intracellular b chains carry the kinase activity
  • Upon stimulation by its ligand, IGF-1 receptor autophosphorylates multiple tyrosine sites in its b chains and phosphorylates other signaling mediators that regulate cell growth, development, and neoplastic transformation.

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Antigen:
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Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

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Phosphorylated Human IGF-1 Receptor Peptide

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50 Tests

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Cell Biology

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Human, Mouse, Rat

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IgG1 κ

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Flow Cytometry

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Affinity Purified

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RUO

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Primary

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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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