BDB558610

Histone H3 (pS28) Rat, Alexa Fluor 488, Clone: HTA28, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB558610-Each-of-1 In Stock ₹ 44,148.96

BDB558610 - Each of 1

₹ 44,148.96

In Stock

Quantity

1

Base Price: ₹ 44,148.96

GST (18%): ₹ 7,946.813

Total Price: ₹ 52,095.773

Antigen

Histone H3 (pS28)

Classification

Monoclonal

Conjugate

Alexa Fluor 488

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

In vitro Assay

Clone

HTA28

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Phosphorylated Human Histone H3 Peptide

Quantity

100 Tests

Research Discipline

Cell Biology

Target Species

Bovine, Fly, Human, Mouse, Rat

Isotype

IgG2a κ

Description

  • Histones are highly basic proteins that complex with DNA to form chromatin
  • Histone H3 is a ∽15kDa protein that is phosphorylated at serine 28 (S28), S10, and/or threonine 11 during mammalian cell mitosis and meiosis
  • The phosphorylation sites are located in the N-terminal tail, a region that is outside of the chromatin fiber and is thus accessible for interactions with agents that may regulate chromatin or specific gene activities
  • The phosphorylation states of the two serine sites during the cell cycle are highly regulated by Aurora B kinase and a PP1 phosphatase: S10 is in the phosphorylated state from late G2 phase to anaphase, while S28 is phosphorylated from prophase to anaphase
  • Furthermore, phosphorylation of histone H3 S28 may be mediated by other kinases in response to external stimuli
  • Evidence suggests that histone phosphorylation is involved in the regulation of chromosome condensation, cell division, and gene transcription
  • The HTA28 monoclonal antibody reacts with histone H3 phosphorylated at S28 in its N-terminal tail
  • It does not recognize the unphosphorylated protein
  • Bioimaging

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BD Biosciences

BDB558610

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Antigen:
Histone H3 (pS28)

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
In vitro Assay

Clone:
HTA28

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Phosphorylated Human Histone H3 Peptide

Quantity:
100 Tests

Research Discipline:
Cell Biology

Target Species:
Bovine, Fly, Human, Mouse, Rat

Isotype:
IgG2a κ

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BD Biosciences

BDB558615

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Antigen:
Ki-67

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
In vitro Assay

Clone:
B56

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human Ki-67

Quantity:
100 Tests

Research Discipline:
Cell Biology

Target Species:
Human, Mouse, Rat, Rhesus Monkey

Isotype:
IgG1 κ

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BD Biosciences

BDB558616

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Antigen:
Ki-67

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
In vitro Assay

Clone:
B56

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human Ki-67

Quantity:
100 Tests

Research Discipline:
Cell Biology

Target Species:
Human, Mouse, Rat, Rhesus Monkey

Isotype:
IgG1 κ

Img

BD Biosciences

BDB558617

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Antigen:
Ki-67

Classification:
Monoclonal

Conjugate:
Alexa Fluor 555

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
In vitro Assay

Clone:
B56

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human Ki-67

Quantity:
100 Tests

Research Discipline:
Cell Biology

Target Species:
Human, Mouse, Rat, Rhesus Monkey

Isotype:
IgG1 κ