BDB558610

Histone H3 (pS28) Rat, Alexa Fluor 488, Clone: HTA28, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB558610-Each-of-1 In Stock ₹ 45,924.00

BDB558610 - Each of 1

₹ 45,924.00

In Stock

Quantity

1

Base Price: ₹ 45,924.00

GST (18%): ₹ 8,266.32

Total Price: ₹ 54,190.32

Antigen

Histone H3 (pS28)

Classification

Monoclonal

Conjugate

Alexa Fluor 488

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

In vitro Assay

Clone

HTA28

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Phosphorylated Human Histone H3 Peptide

Quantity

100 Tests

Research Discipline

Cell Biology

Target Species

Bovine, Fly, Human, Mouse, Rat

Isotype

IgG2a κ

Description

  • Histones are highly basic proteins that complex with DNA to form chromatin
  • Histone H3 is a ∽15kDa protein that is phosphorylated at serine 28 (S28), S10, and/or threonine 11 during mammalian cell mitosis and meiosis
  • The phosphorylation sites are located in the N-terminal tail, a region that is outside of the chromatin fiber and is thus accessible for interactions with agents that may regulate chromatin or specific gene activities
  • The phosphorylation states of the two serine sites during the cell cycle are highly regulated by Aurora B kinase and a PP1 phosphatase: S10 is in the phosphorylated state from late G2 phase to anaphase, while S28 is phosphorylated from prophase to anaphase
  • Furthermore, phosphorylation of histone H3 S28 may be mediated by other kinases in response to external stimuli
  • Evidence suggests that histone phosphorylation is involved in the regulation of chromosome condensation, cell division, and gene transcription
  • The HTA28 monoclonal antibody reacts with histone H3 phosphorylated at S28 in its N-terminal tail
  • It does not recognize the unphosphorylated protein
  • Bioimaging

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BD Biosciences

BDB558610

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Antigen:
Histone H3 (pS28)

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
In vitro Assay

Clone:
HTA28

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Phosphorylated Human Histone H3 Peptide

Quantity:
100 Tests

Research Discipline:
Cell Biology

Target Species:
Bovine, Fly, Human, Mouse, Rat

Isotype:
IgG2a κ

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BD Biosciences

BDB558615

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Antigen:
Ki-67

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
In vitro Assay

Clone:
B56

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human Ki-67

Quantity:
100 Tests

Research Discipline:
Cell Biology

Target Species:
Human, Mouse, Rat, Rhesus Monkey

Isotype:
IgG1 κ

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BD Biosciences

BDB558616

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Antigen:
Ki-67

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
In vitro Assay

Clone:
B56

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human Ki-67

Quantity:
100 Tests

Research Discipline:
Cell Biology

Target Species:
Human, Mouse, Rat, Rhesus Monkey

Isotype:
IgG1 κ

Img

BD Biosciences

BDB558617

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Antigen:
Ki-67

Classification:
Monoclonal

Conjugate:
Alexa Fluor 555

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
In vitro Assay

Clone:
B56

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human Ki-67

Quantity:
100 Tests

Research Discipline:
Cell Biology

Target Species:
Human, Mouse, Rat, Rhesus Monkey

Isotype:
IgG1 κ