BDB558694

CD279 Mouse anti-Human, APC, Clone: MIH4, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB558694-Each-of-1 In Stock ₹ 31,443.30

BDB558694 - Each of 1

₹ 31,443.30

In Stock

Quantity

1

Base Price: ₹ 31,443.30

GST (18%): ₹ 5,659.794

Total Price: ₹ 37,103.094

Antigen

CD279

Classification

Monoclonal

Conjugate

APC

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human PD-1 Transfected Cell Line

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

MIH4

Description

PD-1

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • Reacts with the program death 1 (PD-1) receptor CD279, a member of the Ig superfamily
  • CD279 is an immunoregulatory receptor expressed on activated T cells, B cells and myeloid cells
  • Mice deficient in CD2791 show a breakdown of peripheral tolerance and manifest multiple autoimmune symptoms
  • It contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region
  • PD-L1 and PD-L2 are ligands of CD279 and are members of the B7 gene family
  • Interaction of CD279:PD-Ligands results in inhibition of T cell proliferation and cytokine secretion
  • Reports suggest that the B7/CTLA-4 pathway functions primarily to attenuate, limit, and/or terminate naοve T-cell activation in secondary lymphoid organs
  • The PD-ligand:CD279 pathway, on the other hand, may primarily attenuate, limit, and/or terminate T-, B-, and myeloid cell activation/effector function at sites of inflammation in the periphery.

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BD Biosciences

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Antigen:
CD279

Classification:
Monoclonal

Conjugate:
APC

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human PD-1 Transfected Cell Line

Quantity:
100 Tests

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
MIH4

Description:
PD-1

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
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APC

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
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Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
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Description:
__

Host Species:
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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Formulation:
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Isotype:
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Purification Method:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.