BDB559257

NPM-ALK Set Mouse anti-Human, PE, Clone: ALK1, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB559257-Each-of-1 In Stock ₹ 42,951.12

BDB559257 - Each of 1

₹ 42,951.12

In Stock

Quantity

1

Base Price: ₹ 42,951.12

GST (18%): ₹ 7,731.202

Total Price: ₹ 50,682.322

Antigen

NPM-ALK Set

Classification

Monoclonal

Conjugate

PE

Purification Method

Affinity Purified

Regulatory Status

RUO

Includes

PE Mouse Anti-Human NPM-ALK/ALK (100 tests ), PE Mouse IgG3 Kappa Isotype Control (anti-Fructosan) (100 tests)

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

ALK1

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Isotype

IgG3 κ

Description

  • Reacts with ALK-NPM, a chimeric gene product of approximately 80 kDa, which is the result of t(2;5)(p23;q35) chromosomal translocation
  • The gene at 5q35 encodes for the cell cycle-regulated nucleolar protein, nucleophism (NPM), while the gene at 2p23 encodes a novel receptor tyrosine kinase, anaplastic lymphoma kinase (ALK)
  • The 2;5 translocation results in the expression of NPM-ALK protein, or p80, comprised of the N-terminal portion of NPM (about 40% of the molecule) linked to the entire intracellular portion of ALK
  • ALK1 antibody recognizes a formalin resistant epitope in both the NPM-ALK chimeric and the 200 kDa normal human ALK proteins
  • Cytoplasmic and nuclear expression of NPM-ALK is seen in t(2;5)+ cell lines Su-DHL-1 and Karpas 299
  • This antibody is routinely tested by flow cytometric analysis
  • Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

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Antigen:
NPM-ALK Set

Classification:
Monoclonal

Conjugate:
PE

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Includes:
PE Mouse Anti-Human NPM-ALK/ALK (100 tests ), PE Mouse IgG3 Kappa Isotype Control (anti-Fructosan) (100 tests)

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
ALK1

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG3 κ

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Antigen:
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Classification:
Monoclonal

Conjugate:
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Purification Method:
Affinity Purified

Regulatory Status:
RUO

Includes:
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Content And Storage:
Store undiluted at 4°C

Applications:
Flow Cytometry

Clone:
3A6

Host Species:
Mouse

Quantity:
0.1 mg

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG1 κ

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Antigen:
Ig

Classification:
Polyclonal

Conjugate:
Biotin

Purification Method:
Affinity Purified

Regulatory Status:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
ELISA

Clone:
POLYCLONAL

Host Species:
Goat

Quantity:
0.5 mg

Primary or Secondary:
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Target Species:
Rat

Isotype:
Ig

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Classification:
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Conjugate:
R-PE

Purification Method:
Affinity Purified

Regulatory Status:
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Includes:
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Content And Storage:
Undiluted at 4°C

Applications:
Flow Cytometry

Clone:
MOPC-21

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
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Target Species:
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Isotype:
IgG1 κ