BDB559341

Caspase-3 Rabbit, FITC, Clone: C92-605, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB559341-Each-of-1 In Stock ₹ 37,988.64

BDB559341 - Each of 1

₹ 37,988.64

In Stock

Quantity

1

Base Price: ₹ 37,988.64

GST (18%): ₹ 6,837.955

Total Price: ₹ 44,826.595

Antigen

Caspase-3

Classification

Monoclonal

Conjugate

FITC

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human Active Caspase-3 Fragment

Quantity

100 Tests

Research Discipline

Cell Biology

Target Species

Human, Mouse

Isotype

IgG

Applications

Flow Cytometry

Clone

C92-605

Description

CPP32; Yama; Apopain

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • The caspase family of cysteine proteases plays a key role in apoptosis and inflammation
  • Caspase-3 is a key protease that is activated during the early stages of apoptosis and, like other members of the caspase family, is synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis by self-proteolysis and/or cleavage by another protease
  • The processed forms of caspases consist of large (17-22 kDa) and small (10-12 kDa) subunits which associate to form an active enzyme
  • Active caspase-3, a marker for cells undergoing apoptosis, consists of a heterodimer of 17 and 12 kDa subunits which is derived from the 32 kDa pro-enzyme
  • Active caspase-3 proteolytically cleaves and activates other caspases, as well as relevant targets in the cytoplasm, e.g., D4-GDI and Bcl-2, and in the nucleus (e.g
  • PARP)
  • This antibody has been reported to specifically recognize the active form of caspase-3 in human and mouse cells
  • It has not been reported to recognize the pro-enzyme form of caspase-3.

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BDB559341

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Antigen:
Caspase-3

Classification:
Monoclonal

Conjugate:
FITC

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human Active Caspase-3 Fragment

Quantity:
100 Tests

Research Discipline:
Cell Biology

Target Species:
Human, Mouse

Isotype:
IgG

Applications:
Flow Cytometry

Clone:
C92-605

Description:
CPP32; Yama; Apopain

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
IgA

Classification:
Monoclonal

Conjugate:
FITC

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Pooled mouse IgA

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
C10-3

Description:
__

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
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Classification:
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Conjugate:
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Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

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Quantity:
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Flow Cytometry

Clone:
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Description:
__

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
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Classification:
Monoclonal

Conjugate:
PE-Cyanine5

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
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Quantity:
100 Tests

Research Discipline:
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Target Species:
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Isotype:
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Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.