BDB559829

Qa-1(b) Mouse anti-Mouse, Biotin, Clone: 6A8.6F10.1A6, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB559829-Each-of-1 In Stock ₹ 34,224.00

BDB559829 - Each of 1

₹ 34,224.00

In Stock

Quantity

1

Base Price: ₹ 34,224.00

GST (18%): ₹ 6,160.32

Total Price: ₹ 40,384.32

Antigen

Qa-1(b)

Classification

Monoclonal

Concentration

0.5mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Qa-1(b) aa. 161-179 Peptide

Quantity

0.5 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

6A8.6F10.1A6

Conjugate

Biotin

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • The 6A8.6F10.1A6 monoclonal antibody reacts with the Qa-1(b) alloantigen, which is a nonclassical MHC class I (Class Ib) molecule encoded by the T23 gene of the H-2 complex
  • Qa-1 associates with β2-microglobulin and is expressed at low levels on most leukocytes and many other cell types
  • Its level of cell-surface expression is upregulated by IFNγ or specific peptides
  • Qa-1 is an oligomorphic molecule which presents a limited pool of peptides to T lymphocytes bearing α&β and γδTCR and binds to a large subpopulation of NK cells
  • In fact, Qa-1(b) is the ligand for CD94/NKG2A, CD94/NKG2C, and CD94/NKG2E receptors, which are expressed on NK cells
  • Furthermore, it has been reported that Qa-1 expressed on activated B lymphocytes is involved in immunoregulation by inducing T-cell-mediated suppression of antibody responses
  • The 6A8.6F10.1A6 mAb can detect Qa-1(b) on activated splenocytes from C57BL/6 and BALB/c mice (both Qa-1(b)), but not from A/j mice (Qa-1(a)), and it can block target cell recognition by CTLs specific for Qa-1-presented antigen
  • Flow Cytometry

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BDB559829

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Antigen:
Qa-1(b)

Classification:
Monoclonal

Concentration:
0.5mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Qa-1(b) aa. 161-179 Peptide

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
6A8.6F10.1A6

Conjugate:
Biotin

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
CD21/CD35

Classification:
Monoclonal

Concentration:
1.0mg/mL

Formulation:
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.

Immunogen:
Purified Mouse CR1

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
7G6

Conjugate:
Unconjugated

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

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Antigen:
__

Classification:
__

Concentration:
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Formulation:
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Immunogen:
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Quantity:
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Research Discipline:
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Target Species:
__

Isotype:
IgG2c κ

Applications:
Flow Cytometry

Clone:
A23-1

Conjugate:
R-PE

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
__

Primary or Secondary:
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Content And Storage:
Undiluted at 4°C

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Antigen:
CD134

Classification:
Monoclonal

Concentration:
0.5mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Recombinant Mouse OX-40 3/4 CD4 Chimeric Protein

Quantity:
0.5 mg

Research Discipline:
Immunology

Target Species:
Mouse

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
OX-86

Conjugate:
Unconjugated

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C