BDB559930

BLNK Mouse, Unlabeled, Clone: 2B11, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB559930-Each-of-1 In Stock ₹ 30,288.24

BDB559930 - Each of 1

₹ 30,288.24

In Stock

Quantity

1

Base Price: ₹ 30,288.24

GST (18%): ₹ 5,451.883

Total Price: ₹ 35,740.123

Antigen

BLNK

Classification

Monoclonal

Concentration

0.5mg/mL

Description

SLP-65, BASH, BCA

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human, Mouse

Isotype

IgG2a κ

Applications

Western Blot

Clone

2B11

Conjugate

Unconjugated

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Human N-terminal BLNK Recombinant Protein

Quantity

0.1 mg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

Description

  • B cell activation is initiated by crosslinking the B cell receptor, which leads to activation of non-receptor protein tyrosine kinases (PTK), including Btk, Syk, and three Src kinases, Fyn, Lyn, and Blk
  • Activated PTKs then phosphorylate multiple cellular proteins involved in B lymphocyte signaling
  • Syk is responsible for the tyrosine phosphorylation of B cell l i nk er protein (BLNK), a member of the SLP-76 family of adapter proteins
  • Phosphorylation of human BLNK at tyrosines 84, 178, and 189 (Y84, Y178, and Y189) creates docking sites for PLC g The 2B11 monoclonal antibody recognizes BLNK, regardless of phosphorylation status
  • A fusion protein representing amino acids 4-205 of human BLNK was used as the immunogen
  • BLNK is expressed as two phosphoproteins migrating at 68 and 70 kDa in SDS/PAGE that represent alternatively spliced forms of human BLNK.

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Antigen:
BLNK

Classification:
Monoclonal

Concentration:
0.5mg/mL

Description:
SLP-65, BASH, BCA

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse

Isotype:
IgG2a κ

Applications:
Western Blot

Clone:
2B11

Conjugate:
Unconjugated

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Human N-terminal BLNK Recombinant Protein

Quantity:
0.1 mg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

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Concentration:
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Host Species:
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Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse, Porcine, Rat

Isotype:
IgG2a

Applications:
Western Blot

Clone:
GAD-6

Conjugate:
Unconjugated

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

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Purification Method:
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Clone:
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Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
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0.1 mg

Primary or Secondary:
Primary

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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
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Concentration:
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Description:
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Host Species:
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Purification Method:
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Target Species:
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Clone:
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Conjugate:
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Formulation:
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Immunogen:
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Quantity:
0.1 mg

Primary or Secondary:
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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.