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BDB560002

PTEN Mouse, PE, Clone: A2B1, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB560002-Each-of-1 In Stock ₹ 29,560.98

BDB560002 - Each of 1

₹ 29,560.98

In Stock

Quantity

1

Base Price: ₹ 29,560.98

GST (18%): ₹ 5,320.976

Total Price: ₹ 34,881.956

Antigen

PTEN

Classification

Monoclonal

Conjugate

PE

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human C-terminal PTEN Peptide

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

A2B1

Description

MMAC1, TEP1

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Canine, Human, Mouse, Rat

Isotype

IgG1 κ

Description

  • Cancer can develop when cells escape normal growth control mechanisms through mutations in proto-oncogenes or tumor suppressor genes
  • A characteristic of most oncogene and tumor suppressor gene products is that they are components of signal transduction pathways that are essential for maintaining cellular homeostasis
  • PTEN (phosphatase and tensin homolog), also known as MMAC1 (mutated in multiple advanced cancers 1), is a tumor suppressor gene that is mutated at high frequency in multiple tumor types
  • The protein encoded by PTEN is a phosphatase that preferentially dephosphorylates phosphoinositide substrates
  • It is believed that a mechanism by which PTEN mutations cause tumors is the loss of its negative control on the phosphoinositide 3-kinase signaling pathway that regulates cell growth and survival
  • PTEN also plays a role in the maintenance of hematopoietic stem cells
  • The A2B1 monoclonal antibody recognizes PTEN, regardless of phosphorylation status.

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BD Biosciences

BDB560002

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Antigen:
PTEN
Classification:
Monoclonal
Conjugate:
PE
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human C-terminal PTEN Peptide
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
A2B1
Description:
MMAC1, TEP1
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
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Canine, Human, Mouse, Rat
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IgG1 κ

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Content And Storage:
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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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