BDB560061
E-Cadherin Mouse, Alexa Fluor 488, Clone: 36/E-Cadherin, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB560061-Each-of-1 | In Stock | ₹ 42,951.12 |
BDB560061 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,951.12
GST (18%): ₹ 7,731.202
Total Price: ₹ 50,682.322
Antigen
E-Cadherin
Classification
Monoclonal
Conjugate
Alexa Fluor 488
Formulation
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen
Human E-Cadherin C-terminal Recombinant Protein
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
In vitro Assay
Clone
36/E-Cadherin
Description
CD324; CDH1; CADH1; Cadherin-1; ECAD; CDHE; Arc-1; LCAM; UVO; Uvomorulin
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Canine, Human, Mouse, Rat
Isotype
IgG2a κ
Description
- E-Cadherin is a 120-kDa transmembrane glycoprotein that is localized in the adherens junctions of epithelial cells
- There it interacts with the cytoskeleton through the associated cytoplasmic catenin proteins
- In addition to being a calcium-dependent adhesion molecule, E-Cadherin is also a critical regulator of epithelial junction formation
- Its association with catenins is necessary for cell-cell adhesion
- These E-cadherin/catenin complexes associate with cortical actin bundles at both the zonula adherens and the lateral adhesion plaques
- Tyrosine phosphorylation can disrupt these complexes, leading to changes in cell adhesion properties
- E-Cadherin expression is often down-regulated in highly invasive, poorly differentiated carcinomas
- Increased expression of E-Cadherin in these cells reduces invasiveness
- Thus, loss of expression or function of E-Cadherin appears to be an important step in tumorigenic progression
- The 36/E-Cadherin monoclonal antibody recognizes the cytoplasmic domain of E-Cadherin, regardless of phosphorylation status
- The peptide immunogen was generated from human E-Cadherin aa
- 735-883
- Note: Investigators are advised that this antibody has some degree of cross-reactivity to P-Cadherin.
Compare Similar Items
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Antigen: E-Cadherin
Classification: Monoclonal
Conjugate: Alexa Fluor 488
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen: Human E-Cadherin C-terminal Recombinant Protein
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: In vitro Assay
Clone: 36/E-Cadherin
Description: CD324; CDH1; CADH1; Cadherin-1; ECAD; CDHE; Arc-1; LCAM; UVO; Uvomorulin
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Canine, Human, Mouse, Rat
Isotype: IgG2a κ
Antigen:
E-Cadherin
Classification:
Monoclonal
Conjugate:
Alexa Fluor 488
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen:
Human E-Cadherin C-terminal Recombinant Protein
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
In vitro Assay
Clone:
36/E-Cadherin
Description:
CD324; CDH1; CADH1; Cadherin-1; ECAD; CDHE; Arc-1; LCAM; UVO; Uvomorulin
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Canine, Human, Mouse, Rat
Isotype:
IgG2a κ
Antigen: __
Classification: __
Conjugate: __
Formulation: __
Immunogen: __
Quantity: __
Primary or Secondary: __
Content And Storage: __
Applications: __
Clone: __
Description: __
Host Species: __
Purification Method: __
Regulatory Status: __
Target Species: __
Isotype: __
Antigen:
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Classification:
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Conjugate:
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Formulation:
__
Immunogen:
__
Quantity:
__
Primary or Secondary:
__
Content And Storage:
__
Applications:
__
Clone:
__
Description:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Target Species:
__
Isotype:
__
Antigen: TRA-1-60 Antigen
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human Embryonal Carcinoma Cell Line
Quantity: 0.1 mg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Western Blot
Clone: TRA-1-60
Description: TRA-1-60(R)
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human, Rhesus Monkey
Isotype: IgM κ
Antigen:
TRA-1-60 Antigen
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human Embryonal Carcinoma Cell Line
Quantity:
0.1 mg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Western Blot
Clone:
TRA-1-60
Description:
TRA-1-60(R)
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human, Rhesus Monkey
Isotype:
IgM κ
Antigen: FoxP3
Classification: Monoclonal
Conjugate: PE
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: FoxP3 recombinant protein
Quantity: 25 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 259D/C7
Description: Scurfin, IPEX, JM2
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype: IgG1
Antigen:
FoxP3
Classification:
Monoclonal
Conjugate:
PE
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
FoxP3 recombinant protein
Quantity:
25 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
259D/C7
Description:
Scurfin, IPEX, JM2
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype:
IgG1