BDB560120

SSEA-1 Mouse, Alexa Fluor 647, Clone: MC480, BD

Manufacturer: Fischer Scientific

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Antigen

SSEA-1

Classification

Monoclonal

Conjugate

Alexa Fluor 647

Formulation

Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen

Mouse Teratocarcinoma Cell Line

Quantity

100 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

MC480

Description

3-FAL, X-hapten, LeX antigen, CD15

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human, Mouse

Isotype

IgM κ

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Description

  • The MC480 monoclonal antibody reacts with S tage- S pecific Entigen-1 (SSEA-1), which is a terminal carbohydrate epitope (3-fucosyl-N-acetyllactosamine or 3-FAL) on glycoproteins and lactose series glycolipids
  • SSEA-1 is related to Lewis blood group antigens and is found in a variety of embryonic and adult tissues and cancers
  • As its name implies, the expression of SSEA-1 is stage-specific and can be used to characterize embryonic cells and monitor their differentiation
  • However, its expression pattern differs in the human and mouse
  • In the human, SSEA-1 is not found on embryonic stem (ES) cells, embryonic inner cell mass (ICM), or teratocarcinoma (embryonal carcinoma or EC) cells
  • As human EC and ES cells undergo differentiation, SSEA-1 expression is upregulated
  • In the adult, the same epitope is expressed as CD15 on granulocytes and monocytes, but not lymphocytes or dendritic cells
  • In the mouse, SSEA-1 is found on EC, ES, and primordial germ cells, 8-cell to blastocyst embryos, ICM, and on subpopulations of cells in the adult central nervous system, including stem cells
  • In contrast to the human, SSEA-1 expression is reduced as mouse EC and ES cells undergo differentiation.

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Show Difference

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Fischer Scientific

BDB560120

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Antigen:
SSEA-1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen:
Mouse Teratocarcinoma Cell Line

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
MC480

Description:
3-FAL, X-hapten, LeX antigen, CD15

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse

Isotype:
IgM κ

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BD Biosciences

BDB560123

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Antigen:
TRA-1-81

Classification:
Monoclonal

Conjugate:
Alexa Fluor 555

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen:
Human Embryonal Carcinoma Cell Line

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
In vitro Assay

Clone:
TRA-1-81

Description:
__

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Rhesus Monkey

Isotype:
IgM κ

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BD Biosciences

BDB560126

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Antigen:
SSEA-4

Classification:
Monoclonal

Conjugate:
FITC

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen:
Human Teratocarcinoma Cell Line

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
MC813-70

Description:
Stage-Specific Embryonic Antigen-4

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse

Isotype:
IgG3 κ

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BDB560127

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Antigen:
SSEA-1

Classification:
Monoclonal

Conjugate:
FITC

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Mouse Teratocarcinoma Cell Line

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
MC480

Description:
3-FAL, X-hapten, LeX antigen, CD15

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse

Isotype:
IgM κ