BDB560135
PLC-γ2 Mouse, Alexa Fluor 488, Clone: K86-1161, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB560135-Each-of-1 | In Stock | ₹ 25,282.98 |
BDB560135 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,282.98
GST (18%): ₹ 4,550.936
Total Price: ₹ 29,833.916
Antigen
PLC-γ2
Classification
Monoclonal
Conjugate
Alexa Fluor 488
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
K86-1161
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Phosphorylated Human PLC-γ2 Peptide
Quantity
50 Tests
Research Discipline
Cell Biology
Target Species
Human, Mouse
Isotype
IgG1 κ
Description
- The Phospholipase C (PLC) isozymes hydrolyze phosphatidyl inositol biphosphate to inositol triphosphate and diacylglycerol
- The former causes release of calcium from the endoplasmic reticulum, while the latter is an activator of Protein Kinase C
- Within the PLC family, PLC-g is the only member that contains SH2 and SH3 domains
- These domains enable it to interact with receptor tyrosine kinases and become enzymatically activated via phosphorylation
- It exists as two isoforms: 1) PLC-g1, which is ubiquitously expressed, and 2) PLCg2, found primarily in the lymphoid system
- PLC-g is essential for growth factor-induced cell motility and mitogenesis
- Overexpression of PLC-g is evident in several forms of cancer, and it has been identified as a key mediator of PDGF-dependent cellular transformation
- Thus regulation of PLC-g activity by growth factors is involved in cell growth and transformation
- Although the immunogen for generation of the K86-1161 monoclonal antibody was a phosphorylated peptide, peptide blocking studies demonstrated that the mAb recognizes PLC-g2 regardless of phosphorylation status
- This antibody was raised to a unique region of PLC-γ2 and is predicted not to crossreact with PLC-γ1
- Host Species: Mouse Clone: K86-1161 Isotype: IgG1 κ Species Reactivity: Human Immunogen: Phosphorylated Human PLC-γ2 Peptide Intracellular Staining
Compare Similar Items
Show Difference
Antigen: PLC-γ2
Classification: Monoclonal
Conjugate: Alexa Fluor 488
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: K86-1161
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Phosphorylated Human PLC-γ2 Peptide
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgG1 κ
Antigen:
PLC-γ2
Classification:
Monoclonal
Conjugate:
Alexa Fluor 488
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
K86-1161
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human PLC-γ2 Peptide
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgG1 κ
Antigen: SSEA-1
Classification: Monoclonal
Conjugate: PE
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: MC480
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen: Mouse Teratocarcinoma Cell Line
Quantity: 100 Tests
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgM κ
Antigen:
SSEA-1
Classification:
Monoclonal
Conjugate:
PE
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
MC480
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen:
Mouse Teratocarcinoma Cell Line
Quantity:
100 Tests
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgM κ
Antigen: CD19
Classification: Monoclonal
Conjugate: APC-H7
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 1D3
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: Mouse CD19 Transfected Cell Line
Quantity: 0.1 mg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2a κ
Antigen:
CD19
Classification:
Monoclonal
Conjugate:
APC-H7
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
1D3
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
Mouse CD19 Transfected Cell Line
Quantity:
0.1 mg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2a κ
Antigen: CD4
Classification: Monoclonal
Conjugate: APC-H7
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: RPA-T4
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen: __
Quantity: 100 Tests
Research Discipline: Immunology
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD4
Classification:
Monoclonal
Conjugate:
APC-H7
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
RPA-T4
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen:
__
Quantity:
100 Tests
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG1 κ