BDB560164
PKA RIIα (pS99) Mouse anti-Human, Alexa Fluor 647, Clone: I65-856.286, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB560164-Each-of-1 | In Stock | ₹ 26,166.00 |
BDB560164 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 26,166.00
GST (18%): ₹ 4,709.88
Total Price: ₹ 30,875.88
Antigen
PKA RIIα (pS99)
Classification
Monoclonal
Conjugate
Alexa Fluor 647
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
I65-856.286
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Phosphorylated Human PKA RIIα Peptide
Quantity
50 Tests
Research Discipline
Cell Biology
Target Species
Human
Isotype
IgG1 κ
Description
- cAMP-dependent Protein Kinase (PKA) is composed of two distinct subunits: catalytic (C) and regulatory (R)
- Four regulatory subunits have been identified: RIα, RIβ, RIIα, and RIIβ
- These subunits define type I and II PKAs
- Following binding of cAMP, the regulatory subunits dissociate from the catalytic subunits, rendering the enzyme active
- Type I and II holoenzymes have three potential C subunits (Cα, Cβ, or Cγ)
- Type II PKA can be distinguished by autophosphorylation of the R subunits, while type I PKA binds Mg/ATP with high affinity
- The cAMP-dependent autophosphorylation of the human RIIα subunit occurs at Serine 99 (S99) (Entrez Protein Accession No.CAA33094)
- Most cells express both type I and type II PKAs
- Although the Rα isoforms are ubiquitously expressed, the Rβ isoforms are predominantly found in nervous and adipose tissues
- In addition to their enzyme regulatory activity, the RIIα and RIIβ subunits determine the subcellular location of the holoenzymes via their interactions with specific intracellular anchoring proteins
- The I65-856.286 antibody recognizes human PKA RIIα phosphorylated at S99
- Host Species: Mouse Clone: I65-856.286 Isotype: IgG1 κ Species Reactivity: Human Immunogen: Phosphorylated Human PKA RIIα Peptide Intracellular Staining
Compare Similar Items
Show Difference
Antigen: PKA RIIα (pS99)
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: I65-856.286
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Phosphorylated Human PKA RIIα Peptide
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1 κ
Antigen:
PKA RIIα (pS99)
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
I65-856.286
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human PKA RIIα Peptide
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1 κ
Antigen: __
Classification: __
Conjugate: APC-H7
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: __
Content And Storage: Undiluted at 4°C
Applications: Flow Cytometry
Clone: MOPC-21
Formulation: __
Immunogen: __
Quantity: 0.1 mg
Research Discipline: __
Target Species: Human
Isotype: IgG1 κ
Antigen:
__
Classification:
__
Conjugate:
APC-H7
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
__
Content And Storage:
Undiluted at 4°C
Applications:
Flow Cytometry
Clone:
MOPC-21
Formulation:
__
Immunogen:
__
Quantity:
0.1 mg
Research Discipline:
__
Target Species:
Human
Isotype:
IgG1 κ
Antigen: HLA-ABC
Classification: Monoclonal
Conjugate: PE
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: DX17
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Polyclonal Human NK Cell Line
Quantity: 100 Tests
Research Discipline: Immunology
Target Species: Human
Isotype: IgG1 κ
Antigen:
HLA-ABC
Classification:
Monoclonal
Conjugate:
PE
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
DX17
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Polyclonal Human NK Cell Line
Quantity:
100 Tests
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG1 κ
Antigen: TRA-1-60 Antigen
Classification: Monoclonal
Conjugate: Alexa Fluor 488
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: In vitro Assay
Clone: TRA-1-60
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen: Human Embryonal Carcinoma Cell Line
Quantity: 100 Tests
Research Discipline: Cell Biology
Target Species: Human, Rhesus Monkey
Isotype: IgM κ
Antigen:
TRA-1-60 Antigen
Classification:
Monoclonal
Conjugate:
Alexa Fluor 488
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
In vitro Assay
Clone:
TRA-1-60
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen:
Human Embryonal Carcinoma Cell Line
Quantity:
100 Tests
Research Discipline:
Cell Biology
Target Species:
Human, Rhesus Monkey
Isotype:
IgM κ