BDB560195

CD16 Mouse anti-Human, APC-H7, Clone: 3G8, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB560195-Each-of-1 In Stock ₹ 31,828.32

BDB560195 - Each of 1

₹ 31,828.32

In Stock

Quantity

1

Base Price: ₹ 31,828.32

GST (18%): ₹ 5,729.098

Total Price: ₹ 37,557.418

Antigen

CD16

Classification

Monoclonal

Conjugate

APC-H7

Formulation

Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen

Human polymorphonuclear leukocytes

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

3G8

Description

FcRIII; Fc-gamma RIII; FCG3; FCGR3; FCGRIII; FcγRIII; IGFR3

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 3G8 monoclonal antibody specifically binds to the 50-65 kDa transmembrane form of the IgG Fc Receptor (Fc γRIII), a human NK cell-associated antigen
  • CD16 is expressed on NK cells as well as macrophages and granulocytes
  • Reports indicate that CD16 plays a role in signal transduction and NK cell activation
  • The 3G8 antibody blocks the binding of soluble immune complexes to granulocytes
  • The 3G8 antibody is reported (Vossebeld et al ., 1997) to increase intracellular calcium levels in human neutrophils by interacting with both Fc γRIIa and Fc γRIIIb molecules
  • This antibody has also been reported to induce homotypic neutrophil aggregation
  • This clone also cross-reacts with a subset of peripheral blood lymphocytes and monocytes, but not granulocytes, of baboon and both rhesus and cynomologus macaque monkeys
  • Multi-color analysis reveals that the distribution on lymphocytes is similar to that found in human studies with the majority of CD16-positive lymphocytes being both CD3 and CD20 negative.

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Show Difference

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Fischer Scientific

BDB560195

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Antigen:
CD16

Classification:
Monoclonal

Conjugate:
APC-H7

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen:
Human polymorphonuclear leukocytes

Quantity:
100 Tests

Research Discipline:
Immunology

Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
3G8

Description:
FcRIII; Fc-gamma RIII; FCG3; FCGR3; FCGRIII; FcγRIII; IGFR3

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BDB560197

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Antigen:
__

Classification:
__

Conjugate:
APC-H7

Formulation:
__

Immunogen:
Mouse Pooled Immunoglobulin

Quantity:
0.1 mg

Research Discipline:
__

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
R35-95

Description:
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Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
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Content And Storage:
Undiluted at 4°C

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Monoclonal

Conjugate:
PE

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
__

Quantity:
100 Tests

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
1G10

Description:
__

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Classification:
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Conjugate:
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Formulation:
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Immunogen:
__

Quantity:
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Research Discipline:
__

Target Species:
__

Isotype:
__

Applications:
__

Clone:
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Description:
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Purification Method:
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