BDB560231
p53 (acK382) Mouse anti-Human, Alexa Fluor 647, Clone: L82-51, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB560231-Each-of-1 | In Stock | ₹ 27,036.96 |
BDB560231 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 27,036.96
GST (18%): ₹ 4,866.653
Total Price: ₹ 31,903.613
Antigen
p53 (acK382)
Classification
Monoclonal
Conjugate
Alexa Fluor 647
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human p53 acetylated Peptide
Quantity
50 Tests
Research Discipline
Cell Biology
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
L82-51
Description
TP53 (acK382)
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Description
- The p53 protein is critical to regulation of normal cell growth and proliferation and is a suppressor of tumor cell proliferation
- Inactivation of p53 by a number of mechanisms, such as missense mutations or interaction with oncogenic viral or cellular proteins, can result in tumor progression
- Mutations and/or allelic loss of the p53 gene are associated with a wide variety of human tumors
- Known to have a role in transcriptional regulation, p53 suppresses various promoters containing TATA elements in an apparently sequence-independent fashion
- p53 also binds to DNA in a sequence-specific manner via recognition of a 20-bp consensus-binding site
- This interaction stimulates the expression of genes downstream of the p53 binding site
- A number of genes that contain p53-binding sites have been identified, including MDM2, GADD45, and muscle creatine kinase
- Post-translational acetylation of p53 enhances its DNA-binding activity
- There are multiple factors that affect p53 acetylation, thereby modulating cellular proliferation and apoptosis
- The L82-51 monoclonal antibody recognizes acetylated lysine 382 (acK382) in the C-terminal region of p53
- Host Species: Mouse Clone: L82-51 Isotype: IgG1 κ Species Reactivity: Human Immunogen: Human p53 acetylated Peptide Intracellular Staining
Compare Similar Items
Show Difference
Antigen: p53 (acK382)
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human p53 acetylated Peptide
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: L82-51
Description: TP53 (acK382)
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
p53 (acK382)
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human p53 acetylated Peptide
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
L82-51
Description:
TP53 (acK382)
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: TAZ
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human TAZ Recombinant Protein
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgG2b κ
Applications: Western Blot
Clone: M2-616
Description: WWTR1
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
TAZ
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human TAZ Recombinant Protein
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgG2b κ
Applications:
Western Blot
Clone:
M2-616
Description:
WWTR1
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: SSEA-3
Classification: Monoclonal
Conjugate: FITC
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen: Mouse Embryos
Quantity: 100 Tests
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgM
Applications: Flow Cytometry
Clone: MC631
Description: __
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
SSEA-3
Classification:
Monoclonal
Conjugate:
FITC
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen:
Mouse Embryos
Quantity:
100 Tests
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgM
Applications:
Flow Cytometry
Clone:
MC631
Description:
__
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: SSEA-3
Classification: Monoclonal
Conjugate: PE
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Mouse Embryos
Quantity: 100 Tests
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgM
Applications: Flow Cytometry
Clone: MC631
Description: __
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
SSEA-3
Classification:
Monoclonal
Conjugate:
PE
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Mouse Embryos
Quantity:
100 Tests
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgM
Applications:
Flow Cytometry
Clone:
MC631
Description:
__
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.