BDB560331

IL-21R Mouse anti-Human, APC, Clone: 17A12, BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB560331-Each-of-1 In Stock ₹ 35,592.96

BDB560331 - Each of 1

₹ 35,592.96

In Stock

Quantity

1

Base Price: ₹ 35,592.96

GST (18%): ₹ 6,406.733

Total Price: ₹ 41,999.693

Antigen

IL-21R

Classification

Monoclonal

Conjugate

APC

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human IL-21R Transfected Cell Line

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

17A12

Description

Interleukin-21 receptor; CD360; NILR

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • IL-21 receptor (IL-21R) encodes a 538 amino acid cytokine receptor with an extracellular domain consisting of one copy of the conserved WSXWS -containing cytokine-binding domain
  • The IL-21 receptor combines with the common cytokine-receptor γ-chain to form a functional receptor for IL-21
  • IL-21 is mainly produced by CD4+ T cells
  • IL-21R is preferentially expressed by B cells, T cells, NK cells, some populations of myeloid cells, keratinocytes, and dendritic cells
  • Binding of its ligand, IL-21, in these cells results in the activation of the Jak/Stat signal transduction pathway
  • The effects IL-21 ligand binding has pleiotropic actions such as augmenting the proliferation of T cells, driving of B cells into memory cells, terminally differentiating plasma cells and augmenting the activity of natural killer cells
  • IL-21 receptor has anti-tumor activity and might have a role in the development of autoimmunity; it has been reported that the IL-21 receptor affects the homeostasis of regulatory T cells and it could enhance T cell-activated responses in human immune-inflammatory diseases
  • Host Species: Mouse Clone: 17A12 Isotype: IgG1 κ Species Reactivity: Human Flow Cytometry

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BD Biosciences

BDB560331

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Antigen:
IL-21R

Classification:
Monoclonal

Conjugate:
APC

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human IL-21R Transfected Cell Line

Quantity:
100 Tests

Research Discipline:
Immunology

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
17A12

Description:
Interleukin-21 receptor; CD360; NILR

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BDB560335

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Antigen:
NF-κB p65 (pS529)

Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Phosphorylated Human NF-κB p65 Peptide

Quantity:
50 Tests

Research Discipline:
Cell Biology

Target Species:
Human

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
K10-895.12.50

Description:
transcription factor p65, RELA, MGC131774, NFKB3

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
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Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen:
Rat Nestin aa. 402-604 Recombinant Protein

Quantity:
100 Tests

Research Discipline:
Cell Biology

Target Species:
Human, Rat

Isotype:
IgG1 κ

Applications:
In vitro Assay

Clone:
25/NESTIN

Description:
__

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
Akt (pS473)

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Phosphorylated Human Akt1 (pS473) Peptide

Quantity:
50 Tests

Research Discipline:
Cell Biology

Target Species:
Human, Mouse

Isotype:
IgG1 κ

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Flow Cytometry

Clone:
M89-61

Description:
Akt1, Akt2, Akt3, PKBα, PKBβ, PKBγ, RAC-PKα, RAC-PKβ, RAC-PKγ, STK-2

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.