BDB560428
TLR9 Rat anti-Human, APC, Clone: EB72-1665, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB560428-Each-of-1 | In Stock | ₹ 37,914.00 |
BDB560428 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,914.00
GST (18%): ₹ 6,824.52
Total Price: ₹ 44,738.52
Antigen
TLR9
Classification
Monoclonal
Conjugate
APC
Host Species
Rat
Quantity
100 Tests
Research Discipline
Cell Biology
Target Species
Human
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
EB72-1665
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Description
- Toll-like receptor 9 (TLR9), also designated as CD289, is a type 1 transmembrane glycoprotein (∽110-119kDa calculated molecular weights for protein isoforms) encoded by the TLR9 gene in chromosome 3
- TLR9 is a member of the Toll-like receptor (TLR) family whose members play fundamental roles in pathogen recognition and activation of innate immunity
- TLR9 is highly expressed by plasmacytoid dendritic cells and B cells and at lower levels in some other cell types
- TLR9 is expressed predominantly in the endoplasmic reticulum
- It is recruited to endosomal and lysosomal compartments upon cellular stimulation by bacterial, viral or synthetic DNA molecules that contain unmethylated CpG dinucleotide sequences
- TLR9 generated signals lead to the activation of genes that express type-I interferons and proinflammatory cytokines including IL-6 and IL-12
- TLR9-mediated signaling is also implicated in acquired immune responses as well as in the pathogenesis of autoimmune diseases
- The eB72-1665.1 mAb recognizes the human TLR9 epitope from the peptide sequence, amino acids 273-288
- Host Species: Rat Clone: eB72-1665 Isotype: IgG2a κ Species Reactivity: Human
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Purification Method:
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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: __
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Conjugate: __
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Quantity: __
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Target Species: __
Isotype: __
Applications: __
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Formulation: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
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__
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__
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__
Target Species:
__
Isotype:
__
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__
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__
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__
Purification Method:
__
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__
Primary or Secondary:
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