BDB560628
CD49b (Pan-NK cells) Rat anti-Mouse, APC, Clone: DX5, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB560628-Each-of-1 | In Stock | ₹ 15,640.37 |
BDB560628 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 15,640.37
GST (18%): ₹ 2,815.267
Total Price: ₹ 18,455.637
Antigen
CD49b (Pan NK)
Classification
Monoclonal
Concentration
0.2mg/mL
Description
itga2; Integrin alpha-2; DX5; Pan NK cell marker; VLAA2; VLA-2 alpha chain
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
DX5
Conjugate
APC
Formulation
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen
rIL-2n++agated NK1.1+ cells from C57BL/6 mice
Quantity
50 μg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgM κ
Description
- The rat anti-mouse CD49b monoclonal antibody (clone DX5) specifically binds t o the integrin α2 chain (CD49b)
- C D49b is a 150 kDa transmembrane glycoprotein that non-covalently ass ociates with CD29 (integrin β1) to form the integrin α2β1 complex known as VLA-2
- The rat anti-mouse CD49b antibody (clone DX5) has been reported to identify the majority of NK cells and a small T-cell subpopulation in most mouse strains (e.g., A/J, AKR, BALB/c, C3H/HeJ, C57BL/6, C57BL/10, C57BR, C58, CBA/Ca, DBA/1, DBA/2, SJL, SWR, 129/J, but not NOD)
- The DX5 antibody also recognizes platelets that express high levels of CD49b
- Multiparameter flow cytometric analysis has demonstrated that most lymphocytes which express NK-1.1 (NKR-P1B and NKR-P1C), as detectable by mouse anti-mouse NK-1.1 antibody (clone PK136), also express the DX5 antigen
- Small DX5+ NK-1.1- and DX5- NK-1.1+ cell subsets are found, especially among the CD3-positive cell population
- Some CD49b+ NK cells have been reported to gradually lose reactivity with the rat anti-mouse CD49b antibody (clone DX5) when cultured in the presence of recombinant human IL-2
- The resulting DX5-negative cells have weakened cytotoxic activity when compared to the remaining DX5+ cells
- This indicates that the DX5 antibody distinguishes functional subsets of NK cells
- No activation or blocking activity of the rat anti-mouse antibody (clone DX5) has been observed
- Staining of splenic NK cells with this antibody reportedly can be blocked by hamster anti-mouse CD49b antibody (clone HMα2).
Compare Similar Items
Show Difference
Antigen: CD49b (Pan NK)
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: itga2; Integrin alpha-2; DX5; Pan NK cell marker; VLAA2; VLA-2 alpha chain
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: DX5
Conjugate: APC
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: rIL-2n++agated NK1.1+ cells from C57BL/6 mice
Quantity: 50 μg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgM κ
Antigen:
CD49b (Pan NK)
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
itga2; Integrin alpha-2; DX5; Pan NK cell marker; VLAA2; VLA-2 alpha chain
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
DX5
Conjugate:
APC
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
rIL-2n++agated NK1.1+ cells from C57BL/6 mice
Quantity:
50 μg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgM κ
Antigen: CD20
Classification: Monoclonal
Concentration: __
Description: __
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 2H7
Conjugate: Alexa Fluor 700
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: Human 6.16c1.3 B cell line
Quantity: 50 Tests
Research Discipline: Immunology
Target Species: Human
Isotype: IgG2b κ
Antigen:
CD20
Classification:
Monoclonal
Concentration:
__
Description:
__
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
2H7
Conjugate:
Alexa Fluor 700
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
Human 6.16c1.3 B cell line
Quantity:
50 Tests
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG2b κ
Antigen: CD14
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: __
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: RMC5-3
Conjugate: APC
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Recombinant Mouse CD14
Quantity: 50 μg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
CD14
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
__
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
RMC5-3
Conjugate:
APC
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Recombinant Mouse CD14
Quantity:
50 μg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG1 κ
Antigen: CD14
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Cd14; CD14 antigen; Myeloid cell-specific leucine-rich glycoprotein
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: RMC5-3
Conjugate: APC-Cyanine7
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: Recombinant Mouse CD14
Quantity: 50 μg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
CD14
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Cd14; CD14 antigen; Myeloid cell-specific leucine-rich glycoprotein
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
RMC5-3
Conjugate:
APC-Cyanine7
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
Recombinant Mouse CD14
Quantity:
50 μg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG1 κ