BDB560637
Bcl-2 Mouse anti-Human, V450, Clone: BCL-2/100, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB560637-Each-of-1 | In Stock | ₹ 26,181.36 |
BDB560637 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 26,181.36
GST (18%): ₹ 4,712.645
Total Price: ₹ 30,894.005
Antigen
Bcl-2
Classification
Monoclonal
Conjugate
Violet Fluor 450 (V450)
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
BCL-2/100
Formulation
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen
Human Bcl-2 synthetic peptide aa. 41-54
Quantity
50 Tests
Research Discipline
Cell Biology
Target Species
Human
Isotype
IgG1 κ
Description
- Programmed cell death (apoptosis) is a normal physiologic process which occurs during embryonic development as well as in maintenance of tissue homeostasis
- The apoptotic program is characterized by certain morphological features
- These include changes in the plasma membrane such as loss of membrane asymmetry and attachment, a condensation of the cytoplasm and nucleus, and internucleosomal cleavage of DNA
- In the final stages, the dying cells become fragmented into apoptotic bodies which are rapidly eliminated by phagocytic cells without eliciting significant inflammatory damage to surrounding cells
- Members of the Bcl-2 family play a major role in regulating the response of cells to apoptotic signals
- Bcl-2 is considered to be novel among proto-oncogenes because it blocks apoptosis in many cell types
- Bcl-2 is thought to provide selective survival advantage for cells by blocking apoptosis and thus may contribute to tumorigenesis
- Bcl-2 is a ∽ 26 kDa intracellular, integral membrane protein found primarily in the nuclear envelope, endoplasmic reticulum and outer mitochondrial membrane
- Clone Bcl-2/100 reacts with human Bcl-2
- It has been reported not to cross-react with mouse Bcl-2
- A synthetic peptide corresponding to amino acids 41-54 (GAAPAPGIFSSQPG) of human Bcl-2 was used as the immunogen
- This peptide sequence reportedly is not conserved between human and mouse
- The antibody is conjugated to BD Horizon™ V450, which has been developed for use in multicolor flow cytometry experiments and is available exclusively from BD Biosciences
- It is excited by the Violet laser Ex max of 406nm and has an Em Max at 450 nm
- Conjugates with BD Horizon™ V450 can be used in place of Pacific Blue™ conjugates.
Compare Similar Items
Show Difference
Antigen: Bcl-2
Classification: Monoclonal
Conjugate: Violet Fluor 450 (V450)
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: BCL-2/100
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: Human Bcl-2 synthetic peptide aa. 41-54
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1 κ
Antigen:
Bcl-2
Classification:
Monoclonal
Conjugate:
Violet Fluor 450 (V450)
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
BCL-2/100
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
Human Bcl-2 synthetic peptide aa. 41-54
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD14
Classification: Monoclonal
Conjugate: PerCP-Cyanine5.5
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: RMC5-3
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Recombinant Mouse CD14
Quantity: 50 μg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
CD14
Classification:
Monoclonal
Conjugate:
PerCP-Cyanine5.5
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
RMC5-3
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Recombinant Mouse CD14
Quantity:
50 μg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG1 κ
Antigen: PARP (Asp 214)
Classification: Monoclonal
Conjugate: Alexa Fluor 700
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: F21-852
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: Human cleaved PARP
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1 κ
Antigen:
PARP (Asp 214)
Classification:
Monoclonal
Conjugate:
Alexa Fluor 700
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
F21-852
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
Human cleaved PARP
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD2
Classification: Monoclonal
Conjugate: APC
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: RPA-2.10
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human Phytohemagglutinin-treated Lymphoblasts
Quantity: 50 Tests
Research Discipline: Immunology
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD2
Classification:
Monoclonal
Conjugate:
APC
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
RPA-2.10
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human Phytohemagglutinin-treated Lymphoblasts
Quantity:
50 Tests
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG1 κ