BDB560653
Ly-6A/E Rat anti-Mouse, V450, Clone: D7, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB560653-Each-of-1 | In Stock | ₹ 23,985.50 |
BDB560653 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 23,985.50
GST (18%): ₹ 4,317.39
Total Price: ₹ 28,302.89
Antigen
Ly-6A/E
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Ly-6A/E; Lymphocyte antigen 6A-2/6E-1; Ly-6A.2/Ly-6E.1; Sca-1; TAP
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
D7
Conjugate
Violet Fluor 450 (V450)
Formulation
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen
IL-2-dependent mouse T-cell line CTL-L
Quantity
50 μg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG2a κ
Description
- The D7 antibody reacts with Ly-6A.2 and Ly-6E.1, which are allelic members of the Ly-6 multigene family
- Sca-1 (Ly6A/E), a phosphatidylinositol-anchored protein of about 18kDa, is expressed on the multipotent hematopoietic stem cells (HSC) in the bone marrow of mice with both Ly-6 haplotypes
- In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, C57L, C58, DBA/2, PL, SJL, SWR, 129), Ly-6A/E is also expressed on distinct subpopulations of bone marrow and peripheral B lymphocytes and thymic and peripheral T lymphocytes
- Strains with the Ly-6.1 haplotype (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have few Ly-6A/E+ resting peripheral lymphocytes, whereas activation of lymphocytes from mice of both Ly-6 haplotypes leads to strong expression of the Sca-1 antigen
- Studies with the D7 antibody have demonstrated that Ly-6A/E may be involved in the regulation of B and T lymphocyte responses, and it appears to be required for T-cell receptor-mediated T-cell activation
- Purified E13-161.7 mAb (anti-Ly-6A/E, Mfr
- No
- 553333) can block binding of FITC-conjugated D7 antibody (Mfr
- No
- 557405) to mouse splenocytes, but purified mAb D7 is unable to block binding of FITC-conjugated E13-161.7 antibody (Mfr
- No
- 553335)
- Anti-Ly-6A/E (Sca-1) mAb may be used in combination with the Mouse Lineage Panel (Mfr
- No
- 559971) to identify HSC
- The antibody is conjugated to BD Horizon™ V450, which has been developed for use in multicolor flow cytometry experiments and is available exclusively from BD Biosciences
- It is excited by the Violet laser Ex max of 406 nm and has an Em Max at 450 nm
- Conjugates with BD Horizon™ V450 can be used in place of Pacific Blue™ conjugates
- Flow Cytometry
Compare Similar Items
Show Difference
Antigen: Ly-6A/E
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Ly-6A/E; Lymphocyte antigen 6A-2/6E-1; Ly-6A.2/Ly-6E.1; Sca-1; TAP
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: D7
Conjugate: Violet Fluor 450 (V450)
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: IL-2-dependent mouse T-cell line CTL-L
Quantity: 50 μg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2a κ
Antigen:
Ly-6A/E
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Ly-6A/E; Lymphocyte antigen 6A-2/6E-1; Ly-6A.2/Ly-6E.1; Sca-1; TAP
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
D7
Conjugate:
Violet Fluor 450 (V450)
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
IL-2-dependent mouse T-cell line CTL-L
Quantity:
50 μg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2a κ
Antigen: TCR β Chain
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Tcrb; TCRbeta; TCRβ, T cell receptor beta Chain
Host Species: Hamster
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: H57-597
Conjugate: APC
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: TCR affinity-purified from mouse T-cell hybridoma DO-11.10
Quantity: 50 μg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2
Antigen:
TCR β Chain
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Tcrb; TCRbeta; TCRβ, T cell receptor beta Chain
Host Species:
Hamster
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
H57-597
Conjugate:
APC
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
TCR affinity-purified from mouse T-cell hybridoma DO-11.10
Quantity:
50 μg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2
Antigen: IFN-γ
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: __
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: XMG1.2
Conjugate: PerCP-Cyanine5.5
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse IFN-γ
Quantity: 50 μg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
IFN-γ
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
__
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
XMG1.2
Conjugate:
PerCP-Cyanine5.5
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse IFN-γ
Quantity:
50 μg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG1 κ
Antigen: CD107a
Classification: Monoclonal
Concentration: __
Description: LAMP1; LAMP-1; LAMPA; LGP120
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: H4A3
Conjugate: APC
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human Adult Adherent Peripheral Blood Cells
Quantity: 50 Tests
Research Discipline: Immunology
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD107a
Classification:
Monoclonal
Concentration:
__
Description:
LAMP1; LAMP-1; LAMPA; LGP120
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
H4A3
Conjugate:
APC
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human Adult Adherent Peripheral Blood Cells
Quantity:
50 Tests
Research Discipline:
Immunology
Target Species:
Human
Isotype:
IgG1 κ