BDB560718
CD135 Rat anti-Mouse, APC, Clone: A2F10.1, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB560718-Each-of-1 | In Stock | ₹ 17,009.33 |
BDB560718 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,009.33
GST (18%): ₹ 3,061.679
Total Price: ₹ 20,071.009
Antigen
CD135
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Flt3; Fms-like tyrosine kinase 3; FLT-3; FLK-2; Fetal liver kinase 2; Ly72
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
A2F10.1
Conjugate
APC
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Mouse Flt-3 Transfected Cell Line
Quantity
50 μg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG2a κ
Description
- The A2F10 monoclonal antibody specifically binds to Flk-2/Flt3 (Ly-72, CD135), a receptor protein tyrosine kinase closely related to c-kit, c-fms, and PDGF Receptor of the immunoglobulin superfamily
- The Flt3 message is detected in hematopoietic stem cells and primitive progenitor cells in fetal liver, adult bone marrow, and fetal and adult thymus, as well as brain, placenta, and testis; but it is absent in more mature hematopoietic cells
- In flow cytometric analysis, the A2F10 antibody recognizes Flt3 -transfected Y3 cells (rat myeloma), but not the parent cell line in addition to recognizing early B lymphoid lineage cells in juvenile and adult bone marrow
- A role for CD135 in the regulation of hematopoiesis is suggested by the observations that soluble Flk-2/Flt3 ligand can both stimulate proliferation of stem cell-enriched fetal liver, fetal thymus, and adult bone marrow populations and enhance their responses to other growth factors in vitro
- In addition, injection of Flk-2/Flt3 ligand stimulates extramedullary hematopoiesis in the mouse spleen and accumulation of dendritic cells in the hematopoietic system
- mAb A2F10.1 is reported to immunoprecipitate a 150-kDa surface protein from the murine myeloblast cell line M1, which naturally expresses CD135, and to inhibit the binding of Flk-2/Flt3 ligand to CD135.
Compare Similar Items
Show Difference
Antigen: CD135
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Flt3; Fms-like tyrosine kinase 3; FLT-3; FLK-2; Fetal liver kinase 2; Ly72
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: A2F10.1
Conjugate: APC
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse Flt-3 Transfected Cell Line
Quantity: 50 μg
Research Discipline: Immunology
Target Species: Mouse
Isotype: IgG2a κ
Antigen:
CD135
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Flt3; Fms-like tyrosine kinase 3; FLT-3; FLK-2; Fetal liver kinase 2; Ly72
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
A2F10.1
Conjugate:
APC
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse Flt-3 Transfected Cell Line
Quantity:
50 μg
Research Discipline:
Immunology
Target Species:
Mouse
Isotype:
IgG2a κ
Antigen: IgG2a λ
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: __
Host Species: Rat
Purification Method: __
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: __
Applications: __
Clone: B39-4
Conjugate: APC
Formulation: __
Immunogen: Trinitrophenol-KLH
Quantity: 0.1 mg
Research Discipline: Immunology
Target Species: __
Isotype: IgG2a
Antigen:
IgG2a λ
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
__
Host Species:
Rat
Purification Method:
__
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
__
Applications:
__
Clone:
B39-4
Conjugate:
APC
Formulation:
__
Immunogen:
Trinitrophenol-KLH
Quantity:
0.1 mg
Research Discipline:
Immunology
Target Species:
__
Isotype:
IgG2a
Antigen: IgG2a λ
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: __
Host Species: Rat
Purification Method: __
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: __
Applications: __
Clone: B39-4
Conjugate: PE
Formulation: __
Immunogen: Trinitrophenol-KLH
Quantity: 0.1 mg
Research Discipline: Immunology
Target Species: __
Isotype: IgG2a
Antigen:
IgG2a λ
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
__
Host Species:
Rat
Purification Method:
__
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
__
Applications:
__
Clone:
B39-4
Conjugate:
PE
Formulation:
__
Immunogen:
Trinitrophenol-KLH
Quantity:
0.1 mg
Research Discipline:
Immunology
Target Species:
__
Isotype:
IgG2a
Antigen: IgG2a λ
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: __
Host Species: Rat
Purification Method: __
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: __
Applications: __
Clone: B39-4
Conjugate: PerCP-Cyanine5.5
Formulation: __
Immunogen: Trinitrophenol-KLH
Quantity: 0.1 mg
Research Discipline: Immunology
Target Species: __
Isotype: IgG2a
Antigen:
IgG2a λ
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
__
Host Species:
Rat
Purification Method:
__
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
__
Applications:
__
Clone:
B39-4
Conjugate:
PerCP-Cyanine5.5
Formulation:
__
Immunogen:
Trinitrophenol-KLH
Quantity:
0.1 mg
Research Discipline:
Immunology
Target Species:
__
Isotype:
IgG2a