BDB560795
CD279 Mouse anti-Human, PE, Clone: EH12.1 (also known as EH12), BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB560795-Each-of-1 | In Stock | ₹ 24,769.62 |
BDB560795 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,769.62
GST (18%): ₹ 4,458.532
Total Price: ₹ 29,228.152
Antigen
CD279
Classification
Monoclonal
Conjugate
PE
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human PD-1 Recombinant Protein
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
EH12.1 (also known as EH12)
Description
hPD-1; PD1; PDCD1; Programmed cell death 1; SLEB2
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Description
- The EH12.1 monoclonal antibody specifically binds to CD279
- CD279 is an immunoregulatory receptor that is expressed on activated T cells, B cells and myeloid cells and contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region
- Mice deficient in CD279 show a breakdown of peripheral tolerance and manifest multiple autoimmune symptoms
- PD-L1 and PD-L2 are ligands of CD279 and are members of the B7 gene family
- Interaction of CD279:PD-Ligands results in inhibition of T cell proliferation and cytokine secretion
- Reports suggest that the B7/CTLA-4 pathway functions primarily to attenuate, limit, and/or terminate naοve T-cell activation in secondary lymphoid organs
- The PD-ligand:CD279 pathway, on the other hand, may primarily attenuate, limit, and/or terminate T-, B-, and myeloid cell activation/effector function at sites of inflammation in the periphery.
Compare Similar Items
Show Difference
Antigen: CD279
Classification: Monoclonal
Conjugate: PE
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human PD-1 Recombinant Protein
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: EH12.1 (also known as EH12)
Description: hPD-1; PD1; PDCD1; Programmed cell death 1; SLEB2
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD279
Classification:
Monoclonal
Conjugate:
PE
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human PD-1 Recombinant Protein
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
EH12.1 (also known as EH12)
Description:
hPD-1; PD1; PDCD1; Programmed cell death 1; SLEB2
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: SSEA-4
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen: Human Teratocarcinoma Cell Line
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: MC813-70
Description: Stage-Specific Embryonic Antigen-4
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human, Mouse
Isotype: IgG3 κ
Antigen:
SSEA-4
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen:
Human Teratocarcinoma Cell Line
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
MC813-70
Description:
Stage-Specific Embryonic Antigen-4
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse
Isotype:
IgG3 κ
Antigen: Streptavidin
Classification: __
Conjugate: V450
Formulation: __
Immunogen: __
Quantity: 50 Tests
Primary or Secondary: __
Content And Storage: Store undiluted at 4°C. Protect from prolonged exposure to light. Do not freeze.
Applications: __
Clone: __
Description: __
Host Species: __
Purification Method: __
Regulatory Status: For research use only (RUO)
Target Species: __
Isotype: __
Antigen:
Streptavidin
Classification:
__
Conjugate:
V450
Formulation:
__
Immunogen:
__
Quantity:
50 Tests
Primary or Secondary:
__
Content And Storage:
Store undiluted at 4°C. Protect from prolonged exposure to light. Do not freeze.
Applications:
__
Clone:
__
Description:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
For research use only (RUO)
Target Species:
__
Isotype:
__
Antigen: CD3e
Classification: Monoclonal
Conjugate: Violet Fluor 450 (V450)
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: Mouse T-cell receptor
Quantity: 0.1 mg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: 500A2
Description: CD3ε chain
Host Species: Hamster
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2 κ
Antigen:
CD3e
Classification:
Monoclonal
Conjugate:
Violet Fluor 450 (V450)
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
Mouse T-cell receptor
Quantity:
0.1 mg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
500A2
Description:
CD3ε chain
Host Species:
Hamster
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2 κ