BDB560838

CD279 Mouse anti-Human, Alexa Fluor 647, Clone: EH12.1 (also known as EH12), BD

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB560838-Each-of-1 In Stock ₹ 32,173.50

BDB560838 - Each of 1

₹ 32,173.50

In Stock

Quantity

1

Base Price: ₹ 32,173.50

GST (18%): ₹ 5,791.23

Total Price: ₹ 37,964.73

Antigen

CD279

Classification

Monoclonal

Conjugate

Alexa Fluor 647

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human PD-1 Recombinant Protein

Quantity

100 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

EH12.1 (also known as EH12)

Description

hPD-1; PD1; PDCD1; Programmed cell death 1; SLEB2

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Description

  • The EH12.1 monoclonal antibody specifically binds to CD279
  • CD279 is an immunoregulatory receptor that is expressed on activated T cells, B cells and myeloid cells and contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region
  • Mice deficient in CD279 show a breakdown of peripheral tolerance and manifest multiple autoimmune symptoms
  • PD-L1 and PD-L2 are ligands of CD279 and are members of the B7 gene family
  • Interaction of CD279:PD-Ligands results in inhibition of T cell proliferation and cytokine secretion
  • Reports suggest that the B7/CTLA-4 pathway functions primarily to attenuate, limit, and/or terminate naοve T-cell activation in secondary lymphoid organs
  • The PD-ligand:CD279 pathway, on the other hand, may primarily attenuate, limit, and/or terminate T-, B-, and myeloid cell activation/effector function at sites of inflammation in the periphery.

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BD Biosciences

BDB560838

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Antigen:
CD279

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human PD-1 Recombinant Protein

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
EH12.1 (also known as EH12)

Description:
hPD-1; PD1; PDCD1; Programmed cell death 1; SLEB2

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

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BDB560842

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Antigen:
CD56

Classification:
Monoclonal

Conjugate:
PerCP-Cyanine5.5

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human NK Cells

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
B159

Description:
NCAM1; NCAM-1; Neural cell adhesion molecule 1; NCAM; NKH1; MSK39

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

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Antigen:
CD57

Classification:
Monoclonal

Conjugate:
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Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
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Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
NK-1

Description:
B3GAT1; Beta-1,3-glucuronyltransferase 1; HNK1; LEU7; NK-1; GLCATP; GLCUATP

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgM κ

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Antigen:
CD57

Classification:
Monoclonal

Conjugate:
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Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
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Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
NK-1

Description:
B3GAT1; Beta-1,3-glucuronyltransferase 1; HNK1; LEU7; NK-1; GLCATP; GLCUATP

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgM κ