BDB561021

Ly-6A/E Rat anti-Mouse, PE-Cy7, Clone: D7, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB561021-Each-of-1 In Stock ₹ 13,518.48

BDB561021 - Each of 1

₹ 13,518.48

In Stock

Quantity

1

Base Price: ₹ 13,518.48

GST (18%): ₹ 2,433.326

Total Price: ₹ 15,951.806

Antigen

Ly-6A/E

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Ly-6A/E; Lymphocyte antigen 6A-2/6E-1; Ly-6A.2/Ly-6E.1; Sca-1; TAP

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

D7

Conjugate

PE-Cyanine7

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

IL-2-dependent mouse T-cell line CTL-L

Quantity

25 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The D7 antibody reacts with Ly-6A.2 and Ly-6E.1, which are allelic members of the Ly-6 multigene family
  • Sca-1 (Ly6A/E), a phosphatidylinositol-anchored protein of about 18 kDa, is expressed on the multipotent hematopoietic stem cells (HSC) in the bone marrow of mice with both Ly-6 haplotypes
  • In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, C57L, C58, DBA/2, PL, SJL, SWR, 129), Ly-6A/E is also expressed on distinct subpopulations of bone marrow and peripheral B lymphocytes and thymic and peripheral T lymphocytes
  • Strains with the Ly-6.1 haplotype (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have few Ly-6A/E+ resting peripheral lymphocytes, whereas activation of lymphocytes from mice of both Ly-6 haplotypes leads to strong expression of the Sca-1 antigen
  • Studies with the D7 antibody have demonstrated that Ly-6A/E may be involved in the regulation of B and T lymphocyte responses, and it appears to be required for T-cell receptor-mediated T-cell activation
  • Purified E13-161.7 mAb (anti-Ly-6A/E, Cat
  • No
  • 553333) can block binding of FITC-conjugated D7 antibody (Cat
  • No
  • 557405) to mouse splenocytes, but purified mAb D7 is unable to block binding of FITC-conjugated E13-161.7 antibody (Cat
  • No
  • 553335)
  • Anti-Ly-6A/E (Sca-1) mAb may be used in combination with the Mouse Lineage Panel (Cat
  • No
  • 559971) to identify HSC.

Compare Similar Items

Show Difference

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Fischer Scientific

BDB561021

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Antigen:
Ly-6A/E

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Ly-6A/E; Lymphocyte antigen 6A-2/6E-1; Ly-6A.2/Ly-6E.1; Sca-1; TAP

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
D7

Conjugate:
PE-Cyanine7

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
IL-2-dependent mouse T-cell line CTL-L

Quantity:
25 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BDB561022

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Antigen:
CD11c

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Cd11c; Itgax; Integrin alpha-X; Integrin αX; Cr4; Complement receptor 4

Host Species:
Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1 λ2

Applications:
Flow Cytometry

Clone:
HL3

Conjugate:
PE-Cyanine7

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
C57BL/6 Mouse Intestinal Intraepithelial Lymphocytes

Quantity:
25 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BDB561024

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Antigen:
IFN-γ

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
__

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
B27

Conjugate:
Alexa Fluor 700

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen:
Human IFN-γ Recombinant Protein

Quantity:
25 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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BDB561025

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Antigen:
CD4

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
Cd4; CD4 antigen; L3T4; Ly-4; T-cell surface antigen T4/Leu-3

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
RM4-5

Conjugate:
Alexa Fluor 700

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen:
Mouse Thymocytes (BALB/c)

Quantity:
25 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.