BDB561035
CD279 Mouse anti-Human, FITC, Clone: MIH4, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB561035-Each-of-1 | In Stock | ₹ 11,003.02 |
BDB561035 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 11,003.02
GST (18%): ₹ 1,980.544
Total Price: ₹ 12,983.564
Antigen
CD279
Classification
Monoclonal
Concentration
0.5mg/mL
Description
PD-1; hPD-1; PD1; PDCD1; Programmed cell death 1; SLEB2
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
MIH4
Conjugate
FITC
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Human PD-1 Transfected Cell Line
Quantity
25 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Description
- The MIH4 monoclonal antibody specifically binds to the program death 1 (PD-1) receptor CD279, a member of the Ig superfamily
- CD279 is an immunoregulatory receptor expressed on activated T cells, B cells and myeloid cells
- Mice deficient in CD279 show a breakdown of peripheral tolerance and manifest multiple autoimmune symptoms
- It contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region
- PD-L1 and PD-L2 are ligands of CD279 and are members of the B7 gene family
- Interaction of CD279:PD-Ligands results in inhibition of T cell proliferation and cytokine secretion
- Reports suggest that the B7/CTLA-4 pathway functions primarily to attenuate, limit, and/or terminate naοve T-cell activation in secondary lymphoid organs
- The PD-ligand:CD279 pathway, on the other hand, may primarily attenuate, limit, and/or terminate T-, B-, and myeloid cell activation/effector function at sites of inflammation in the periphery.
Compare Similar Items
Show Difference
Antigen: CD279
Classification: Monoclonal
Concentration: 0.5mg/mL
Description: PD-1; hPD-1; PD1; PDCD1; Programmed cell death 1; SLEB2
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: MIH4
Conjugate: FITC
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human PD-1 Transfected Cell Line
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD279
Classification:
Monoclonal
Concentration:
0.5mg/mL
Description:
PD-1; hPD-1; PD1; PDCD1; Programmed cell death 1; SLEB2
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
MIH4
Conjugate:
FITC
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human PD-1 Transfected Cell Line
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: IFN-γ
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: __
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: 4S.B3
Conjugate: PE-Cyanine7
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Human IFN-γ from supernatants of S. aureus-stimulated PBMC
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
IFN-γ
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
__
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
4S.B3
Conjugate:
PE-Cyanine7
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Human IFN-γ from supernatants of S. aureus-stimulated PBMC
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD45
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Ptprc; CD45R; LCA; Leukocyte common antigen; T200; B220; Ly-5; Lyt-4
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2b κ
Applications: Flow Cytometry
Clone: 30-F11
Conjugate: APC-Cyanine7
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Mouse Thymus / Spleen
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD45
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Ptprc; CD45R; LCA; Leukocyte common antigen; T200; B220; Ly-5; Lyt-4
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
30-F11
Conjugate:
APC-Cyanine7
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Mouse Thymus / Spleen
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD25
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Interleukin-2 receptor alpha chain; IL-2RA; IL-2Rα; Il2ra; IL-2R p55
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1 λ
Applications: Flow Cytometry
Clone: PC61
Conjugate: APC-Cyanine7
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: IL-2-dependent cytolytic mouse T-cell clone B6.1
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD25
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Interleukin-2 receptor alpha chain; IL-2RA; IL-2Rα; Il2ra; IL-2R p55
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 λ
Applications:
Flow Cytometry
Clone:
PC61
Conjugate:
APC-Cyanine7
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
IL-2-dependent cytolytic mouse T-cell clone B6.1
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.