BDB561076
Ly-6A/E Rat anti-Mouse, PE, Clone: E13-161.7, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB561076-Each-of-1 | In Stock | ₹ 7,563.50 |
BDB561076 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 7,563.50
GST (18%): ₹ 1,361.43
Total Price: ₹ 8,924.93
Antigen
Ly-6A/E
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Sca-1
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
E13-161.7
Conjugate
PE
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
BALB/c mouse-derived pre-T cell hybridoma
Quantity
25 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Description
- The E13-161.7 antibody reacts with Ly-6A.2 and Ly-6E.1, which are allelic members of the Ly-6 multigene family
- Sca1 (Ly-6A/E), a phosphatidylinositol-anchored protein of about 18 kDa, is expressed on the multipotent hematopoietic stem cell (HSC) in mice with both Ly-6 haplotypes
- Sca-1+ HSC are found in the adult bone marrow and fetal liver, but not in the early embryo yolk sac or intraembryonic hematopoietic sites, and can be mobilized to the peripheral blood and spleen in the adult
- In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, C57L, C58, DBA/2, PL, SJL, SWR, 129), Ly-6A/E is also expressed on distinct subpopulations of bone marrow and peripheral B lymphocytes, myeloid cells, and thymic and peripheral T lymphocytes, on the earliest intrathymic T-cell precursor population, and in several non-hematopoietic tissues
- Strains with the Ly-6.1 haplotype (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have few Ly-6A/E+ resting peripheral lymphocytes, whereas activation of T cells from mice of both Ly-6 haplotypes leads to strong expression of the Sca-1 antigen
- Studies with the D7 antibody (Cat
- No
- 557403) have demonstrated that Ly-6A/E may be involved in the regulation of B and T lymphocyte responses, and it appears to be required for T-cell receptor-mediated T-cell activation
- Purified E13-161.7 mAb can block binding of FITC-conjugated D7 antibody (anti-Ly-6A/E, Cat
- No
- 557405) to mouse splenocytes, but purified mAb D7 (Cat
- No
- 557403) is unable to block binding of FITC-conjugated E13-161.7 antibody (Cat
- No
- 553335)
- Anti-Ly-6A/E (Sca-1) mAb may be used in combination with the Mouse Lineage Panel (Cat
- No
- 559971) to identify HSC.
Compare Similar Items
Show Difference
Antigen: Ly-6A/E
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: Sca-1
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: E13-161.7
Conjugate: PE
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: BALB/c mouse-derived pre-T cell hybridoma
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Ly-6A/E
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
Sca-1
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
E13-161.7
Conjugate:
PE
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
BALB/c mouse-derived pre-T cell hybridoma
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: Ly-6A/E
Classification: Monoclonal
Concentration: 0.5mg/mL
Description: Sca-1
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: E13-161.7
Conjugate: FITC
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: BALB/c mouse-derived pre-T cell hybridoma
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Ly-6A/E
Classification:
Monoclonal
Concentration:
0.5mg/mL
Description:
Sca-1
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
E13-161.7
Conjugate:
FITC
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
BALB/c mouse-derived pre-T cell hybridoma
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: TCR β chain
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: __
Host Species: Hamster
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2 λ1
Applications: Flow Cytometry
Clone: H57-597
Conjugate: APC
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: TCR affinity-purified from mouse T-cell hybridoma DO-11.10
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
TCR β chain
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
__
Host Species:
Hamster
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2 λ1
Applications:
Flow Cytometry
Clone:
H57-597
Conjugate:
APC
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
TCR affinity-purified from mouse T-cell hybridoma DO-11.10
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: TCR β chain
Classification: Monoclonal
Concentration: 0.2mg/mL
Description: __
Host Species: Hamster
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG2 λ1
Applications: Flow Cytometry
Clone: H57-597
Conjugate: PE
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: TCR affinity-purified from mouse T-cell hybridoma DO-11.10
Quantity: 25 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
TCR β chain
Classification:
Monoclonal
Concentration:
0.2mg/mL
Description:
__
Host Species:
Hamster
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG2 λ1
Applications:
Flow Cytometry
Clone:
H57-597
Conjugate:
PE
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
TCR affinity-purified from mouse T-cell hybridoma DO-11.10
Quantity:
25 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.