BDB561142

Granzyme B Mouse anti-Human, PE, Clone: GB11, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB561142-Each-of-1 In Stock ₹ 28,534.26

BDB561142 - Each of 1

₹ 28,534.26

In Stock

Quantity

1

Base Price: ₹ 28,534.26

GST (18%): ₹ 5,136.167

Total Price: ₹ 33,670.427

Antigen

Granzyme B

Classification

Monoclonal

Conjugate

PE

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human Granzyme B

Quantity

100 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

GB11

Description

GZMB; Granzyme-2; CCPI; CGL1; CSPB; CTLA1; CTSGL1; GRB; HLP; SECT

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Description

  • Description The GB11 antibody specifically reacts with human granzyme B, a serine protease ofapproximately 32 kDa
  • Granzyme B is stored in the granules of cytotoxic T lymphocytes and NK cells along with the pore-forming protein perforin
  • In the classic model of target cell lysis, perforins create holes in the target cell membrane allowing entrance of granzymes
  • Granzyme B has been shown to act on specific substrates including caspase-3, -7, -9, and -10 which in turn give rise to enzymes that mediate apoptosis
  • Granzyme B may also be involved in the hydrolysis of extracellular matrix components
  • Detectable levels of granzyme B have been detected in sera from healthy volunteers
  • The immunogen used to generate the GB11 hybridoma was human granzyme B isolated from an NK cell line.

Compare Similar Items

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BD Biosciences

BDB561142

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Antigen:
Granzyme B

Classification:
Monoclonal

Conjugate:
PE

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Human Granzyme B

Quantity:
100 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
GB11

Description:
GZMB; Granzyme-2; CCPI; CGL1; CSPB; CTLA1; CTSGL1; GRB; HLP; SECT

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB561143

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Antigen:
CD197

Classification:
Monoclonal

Conjugate:
Alexa Fluor 700

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Immunogen:
Human CCR7 Transfected Cell Line

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
150503

Description:
CC chemokine receptor 7; BLR2; CMKBR7; EBI1; EVI1; MIP-3 beta receptor

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a

Img

BD Biosciences

BDB561144

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Antigen:
CD197

Classification:
Monoclonal

Conjugate:
PerCP-Cyanine5.5

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen:
Human CCR7 Transfected Cell Line

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
150503

Description:
CC chemokine receptor 7; BLR2; CMKBR7; EBI1; EVI1; MIP-3 beta receptor

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a

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BD Biosciences

BDB561145

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Antigen:
SSEA-3

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Immunogen:
Mouse Embryos

Quantity:
50 Tests

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
MC-631 (also known as MC631)

Description:
__

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse

Isotype:
IgM