BDB561273
CD279 (PD-1) Mouse anti-Human, PerCP-Cy5.5, Clone: EH12.1 (also known as EH12), BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB561273-Each-of-1 | In Stock | ₹ 33,197.28 |
BDB561273 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 33,197.28
GST (18%): ₹ 5,975.51
Total Price: ₹ 39,172.79
Antigen
CD279 (PD-1)
Classification
Monoclonal
Conjugate
PerCP-Cyanine5.5
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human PD-1 Recombinant Protein
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
EH12.1 (also known as EH12)
Description
hPD-1; PD1; PDCD1; Programmed cell death 1; SLEB2
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Description
- The EH12.1 monoclonal antibody specifically binds to CD279
- CD279 is an immunoregulatory receptor that is expressed on activated T cells, B cells and myeloid cells and contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region
- Mice deficient in CD279 show a breakdown of peripheral tolerance and manifest multiple autoimmune symptoms
- PD-L1 and PD-L2 are ligands of CD279 and are members of the B7 gene family
- Interaction of CD279:PD-Ligands results in inhibition of T cell proliferation and cytokine secretion
- Reports suggest that the B7/CTLA-4 pathway functions primarily to attenuate, limit, and/or terminate naοve T-cell activation in secondary lymphoid organs
- The PD-ligand:CD279 pathway, on the other hand, may primarily attenuate, limit, and/or terminate T-, B-, and myeloid cell activation/effector function at sites of inflammation in the periphery.
Compare Similar Items
Show Difference
Antigen: CD279 (PD-1)
Classification: Monoclonal
Conjugate: PerCP-Cyanine5.5
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Human PD-1 Recombinant Protein
Quantity: 100 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: EH12.1 (also known as EH12)
Description: hPD-1; PD1; PDCD1; Programmed cell death 1; SLEB2
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD279 (PD-1)
Classification:
Monoclonal
Conjugate:
PerCP-Cyanine5.5
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Human PD-1 Recombinant Protein
Quantity:
100 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
EH12.1 (also known as EH12)
Description:
hPD-1; PD1; PDCD1; Programmed cell death 1; SLEB2
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: Ki-67
Classification: Monoclonal
Conjugate: Alexa Fluor 700
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: Human Ki-67
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: B56
Description: MKI67; Antigen identified by monoclonal antibody Ki-67; KIA
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human, Mouse, Rat, Rhesus Monkey
Isotype: IgG1 κ
Antigen:
Ki-67
Classification:
Monoclonal
Conjugate:
Alexa Fluor 700
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
Human Ki-67
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
B56
Description:
MKI67; Antigen identified by monoclonal antibody Ki-67; KIA
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human, Mouse, Rat, Rhesus Monkey
Isotype:
IgG1 κ
Antigen: MIP-1b
Classification: Monoclonal
Conjugate: Alexa Fluor 700
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen: Recombinant Human MIP-1β
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: D21-1351
Description: Macrophage inflammatory protein 1-beta; CCL4; C-C motif chemokine 4; LAG-1
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
MIP-1b
Classification:
Monoclonal
Conjugate:
Alexa Fluor 700
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen:
Recombinant Human MIP-1β
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
D21-1351
Description:
Macrophage inflammatory protein 1-beta; CCL4; C-C motif chemokine 4; LAG-1
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: MIP-1b
Classification: Monoclonal
Conjugate: APC-H7
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen: Recombinant Human MIP-1β
Quantity: 50 Tests
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: D21-1351
Description: Macrophage inflammatory protein 1-beta; CCL4; C-C motif chemokine 4; LAG-1
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
MIP-1b
Classification:
Monoclonal
Conjugate:
APC-H7
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen:
Recombinant Human MIP-1β
Quantity:
50 Tests
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
D21-1351
Description:
Macrophage inflammatory protein 1-beta; CCL4; C-C motif chemokine 4; LAG-1
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ